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The S:t Göran Bipolar project


A prospective longitudinal study of bipolar syndromes

In the S:t Göran Bipolar project (SBP) patients diagnosed with bipolar disorder are meticulously phenotyped and followed over time. This enables the identification of clinically relevant subgroups and markers and provides unique possibilities to study disease mechanisms. The short term goal is to further study disease mechanisms in bipolar disorder. However, the long term aim is to identify factors and markers that are predictive of relapse, treatment response, side effects, cognitive and psychosocial functioning and quality of life for individuals suffering from bipolar syndromes. The study participants are investigated using diagnostic, neuropsychological, neurological, imaging, genetic and biochemical approaches. To enable genetic and biochemical analyses and to secure future research goals samples of whole blood, serum and cerebrospinal fluid are stored at KI-Biobank.
SBP includes patients who after thorough diagnostic evaluation are found to suffer from a bipolar syndrome and provide written agreement of participation. Patients are currently recruited from Affektivt centrum, Norra Stockholms psykiatri and from 2009 also from Affektiva enheten in Mölndal. Annual follow-ups are carried out and after 7 years blood and cerebrospinal fluid sampling, imaging and the neuropsychological tests are repeated. The goal is to follow the patients throughout life.

Page Manager: Webbredaktör|Last update: 10/26/2016
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