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Research using brain imaging techniques is conducted in order to investigate structural and functional brain changes in mild cognitive impairment, and early stages of dementia.

We use magnetic resonance imaging (MRI) to study structures in the medial temporal lobe such as the hippocampus. The hippocampus is a plastic structure with a key role in memory functions. Atrophy of the hippocampus and its surrounding structures are well known to predict progression from MCI to Alzheimer’s dementia. Cerebrovascular tissue damage in the brains white matter, white matter changes (WMC), are also investigated. White matter changes are among the most common known disease processes in the brain, and serve as a biomarker for small vessel disease (arteriolosclerosis). White matter changes not only increase the risk of stroke, but may also lead to progressive cognitive decline and dementia. Method development to optimize assessment of structural changes is also a part of the groups work.

The blood flow of the brain can be measured using SPECT technique. The group is currently conducting a research project investigating the link between reduced blood flow in and atrophy of specific brain structures.


Erik Olsson, Niklas Klasson, Anna Molinder, Carl Eckerström, and Mårten Carlsson at an Imaging Cognitive Impairment Network (ICINET) meeting in Lund.

Erik Olsson, Niklas Klasson, Anna Molinder, Carl Eckerström & Mårten Carlsson.

Contact Information

Anders Wallin, professor

Wallinsgatan 6, 431 41 Mölndal

+46 (0) 31 343 10 00



Illustrations: Jacob Stålhammar.

Page Manager: Webbredaktör|Last update: 5/7/2014

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