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Petronella Kettunen


Petronella Kettunen

Postal Address: Su sahlgrenska, 41345 Göteborg
Visiting Address: Klin kem lab , Göteborg

Department of Psychiatry and Neurochemistry at Institute of Neuroscience and Physiology (More Information)
Blå stråket 15, vån 3 SU/Sahlgrenska
413 45 Göteborg
031-342 10 00
Visiting Address: Blå stråket 15, vån 3 SU/Sahlgrenska , 413 45 Göteborg

About Petronella Kettunen

Associate professor Petronella Kettunen received a PhD in medicine (Neuroscience) at the Karolinska Institutet in 2004. She is leading a research group at Institute of Neuroscience and Physiology, is the co-director of Centre for Cognitive Medicine, and a senior visiting researcher at University of Oxford.

Read about the research in the Kettunen lab: http://www.akademiliv.se/en/2018/04/49398/

Current research in the Kettunen lab:

1. Molecular and cellular mechanisms of learning and memory

We are studying the molecular and cellular events that underlie learning. To this end, we are using the zebrafish (Danio rerio) and combining transgenic and molecular methods, behavioral experiments, in vivo calcium imaging and optogenetics. 

2. Pathways underlying memory impairments and neurodegeneration in Alzheimer’s disease

We are interested in understanding how the Alzheimer’s disease-related peptide, amyloid beta, is preventing memory formation in vivo. We are also studying the processes of amyloid-beta-mediated neurodegeneration.

3. The role of microglia in Alzheimer’s disease

In our preparation, we are able to follow the dynamics of microglia, i.e. the immune cells of the brain. In this way, we hope to increase our understanding of the process of amyloid beta clearance and the role of inflammation in Alzheimer’s disease.

4. Neuronal networks underlying social behavior

In collaboration with the Westberg lab at Sahlgrenska Academy, we are investigating the molecular pathways and transmitter systems underlying social behavior.

Lab web pages: 



Twitter: kettunenlab

Dr Kettunen is also the initiator and organizer of the PhD student course Learning and memory – from synapses to memory tests, 3 higher education credits at University of Gothenburg. Course code SN00016.

Funding sources:

•Horizon 2020

•Grass Foundation

•ALF clinical project grants
•Anér Foundation
•Alzheimer foundation
•Brain Foundation
•Capio Research Foundation
•Hedström Foundation
•Hellmuth Hertz Foundation
•Iris Jonzén-Sandblom and Greta Jonzén Foundation
•Wilhelm and Martina Lundgren Foundation
•Längmanska Foundation
•Markus Borgström Foundation
•National Board of Health and Welfare
•Nilsson-Ehle donations
•O. E. and Edla Johansson Science Foundation
•Region Västra Götaland
•Stiftelsen för Gamla Tjänarinnor
•Swedish Society for Medical Research
•Swedish Research Council
•Tore Nilson Foundation for Medical Research
•Torsten Söderberg Foundation
•Wenner-Gren Foundations
•Åhlén Foundation
•Åke Wiberg Foundation

Latest publications

Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort.
Sarah Westwood, Alison L Baird, Sneha N Anand, Alejo J Nevado-Holgado, Andrey Kormilitzin et al.
Journal of Alzheimer's disease : JAD, Journal article 2020
Journal article

Oxytocin Receptors Regulate Social Preference in Zebrafish.
Jenny Landin, Daniel Hovey, Bo Xu, David Lagman, Anna Zettergren et al.
Scientific reports, Journal article 2020
Journal article

Calcium Imaging in the Zebrafish.
Petronella Kettunen
Calcium Signaling. Advances in experimental medicine and biology. Islam M. (red.), Springer, Chapter in book 2020
Chapter in book

A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort.
Daniel Stamate, Min Kim, Petroula Proitsi, Sarah Westwood, Alison Baird et al.
Alzheimer's & dementia (New York, N. Y.), Journal article 2019
Journal article

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay.
Liu Shi, Sarah Westwood, Alison L Baird, Laura Winchester, Valerija Dobricic et al.
Alzheimer's & dementia : the journal of the Alzheimer's Association, Journal article 2019
Journal article

Inflammatory biomarkers in Alzheimer's disease plasma.
Angharad R Morgan, Samuel Touchard, Claire Leckey, Caroline O'Hagan, Alejo J Nevado-Holgado et al.
Alzheimer's & dementia : the journal of the Alzheimer's Association, Journal article 2019
Journal article

Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort.
Min Kim, Stuart Snowden, Tommi Suvitaival, Ashfaq Ali, David J Merkler et al.
Alzheimer's & dementia : the journal of the Alzheimer's Association, Journal article 2019
Journal article

Showing 21 - 30 of 30


Characterization and Expression of the Zebrafish qki Paralogs
Katarzyna J. Radomska, Jonathan Sager, Bryn Farnsworth, Åsa Tellgren-Roth, Giulia Tuveri et al.
PLoS ONE, Journal article 2016
Journal article


A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos
David Bliman, Jesper Nilsson, Petronella Kettunen, Joakim Andréasson, Morten Grøtli
Scientific Reports, Journal article 2015
Journal article



A novel ARC gene polymorphism is associated with reduced risk of Alzheimer's disease
Sara Landgren, Malin von Otter, Mona Seibt Palmér, Caroline Zetterström, Staffan Nilsson et al.
Journal of Neural Transmission, Journal article 2012
Journal article

Calcium imaging in the zebrafish.
Petronella Kettunen
Calcium Signaling. Advances in Experimental Medicine and Biology, Vol. 740, Ed. Shahidul Islam, Springer, Chapter in book 2012
Chapter in book


Neural circuit activity in freely behaving zebrafish (Danio rerio).
Fadi A Issa, Georgeann O'Brien, Petronella Kettunen, Alvaro Sagasti, David L Glanzman et al.
The Journal of experimental biology, Journal article 2011
Journal article


Showing 21 - 30 of 30

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Utskriftsdatum: 2020-07-15