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Developmental Neuroscience Group

Principal Investigator: Xiaoyang Wang

Perinatal brain injury is one of the main causes of cerebral palsy and is strongly associated with sensory, cognitive, and psychological disturbances in children such as autism-spectrum disorders and attention-deficit/hyperactivity disorders. Studies from us and others have suggested roles for hypoxia-ischemia, inflammation, apoptosis, mitochondrial dysfunction, excitotoxicity, impaired oligodendrocyte maturation, other developmental immaturities due to preterm birth, and genetic factors in perinatal brain injury and cerebral palsy; however, we still do not fully understand the mechanisms behind injury development and progression, and there are still no effective preventions or treatments.


The ultimate goal of our research is to fundamentally advance our knowledge of the key factors that impact on brain development and injury processes in the perinatal period and to generate prevention/treatment modalities for perinatal brain injury and cerebral palsy. In particular, our research is mainly focused on the following topics:

  1. The key immune components and immune responses in perinatal brain injury.
  2. The factors that modulate the development of oligodendrocytes and white matter injury.
  3. The effects of intracranial hemorrhage in newborn infants.
  4. The genetic influences on the occurrence of cerebral palsy.

 

Porträttfotografi - Xiaoyang Wang

Xiaoyang Wang

Principal Investigator
M.D. Ph.D. Associate professor

Publications GUP

Contact
Phone: +46 (0)31-786 3260
xiaoyang.wang@fysiologi.gu.se
Visiting and postal addresses

Page Manager: Annie Sundling|Last update: 10/10/2019
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