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John-Olov Jansson

Professor

John-Olov Jansson
Professor
john-olov.jansson@medic.gu.se
+46 31 786 3526
+46 (0)739-011122

Room number: 3413
Postal Address: Box 432, 40530 Göteborg
Visiting Address: Medicinaregatan 11 , 41390 Göteborg


Department of Physiology at Institute of Neuroscience and Physiology (More Information)
Box 432
405 30 Göteborg
Visiting Address: Medicinaregatan 11-13 , 405 30 Göteborg

About John-Olov Jansson

Research group
Immunometabolism Group

Teaching
Endocrinology for medical students and pharmacy students for more than 10 years. Since 2009 course leader for “BF2”, a course introducing scientific techniques and principles to medical students,

Research interest
Importance of brain components of the immune system, such as interleukin-6 (IL-6) och IL-1, for regulation of body fat.

Ongoing research / projects
We have recently found that Glucagon-like peptide-1 (GLP-1) suppresses body fat mass via interleukin-6 (IL-6) in the brain. This is a great interest since we have long-term interest in the metaolic of IL-6 and since GLP-1 analogues, such as exendin-4 (Byetta sand Bydureon) and liraglutide (Victoza and Saxenda) are widely used for treatment of type 2 diabetes and obesity. Surprisingly little has been known about the mechanism of action of this important group of drugs.

Related publications (PubMed):


 

Latest publications

Hyperandrogenism and insulin resistance contribute to hepatic steatosis and inflammation in female rat liver.
Yuehui Zhang, Fanci Meng, Xiaoyan Sun, Xue Sun, Min Hu et al.
Oncotarget, Journal article 2018
Journal article

Hyperandrogenism and insulin resistance contribute to hepatic steatosis and inflammation in female rat liver.
Yuehui Zhang, Fanci Meng, Xiaoyan Sun, Xue Sun, Min Hu et al.
Oncotarget, Journal article 2018
Journal article

Deficiency of liver-derived insulin-like growth factor-I (IGF-I) does not interfere with the skin wound healing rate
I. R. Botusan, X. Zheng, S. Narayanan, J. Grünler, V. G. Sunkari et al.
PLoS ONE, Journal article 2018
Journal article

Body weight homeostat that regulates fat mass independently of leptin in rats and mice.
John-Olov Jansson, Vilborg Palsdottir, Daniel Hägg, Erik Schéle, Suzanne L. Dickson et al.
Proceedings of the National Academy of Sciences of the United States of America, Journal article 2018
Journal article

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
Mariaelisa Graff, Robert A Scott, Anne E Justice, Kristin L Young, Mary F Feitosa et al.
PLoS genetics, Journal article 2017
Journal article

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
M Carola Zillikens, Serkalem Demissie, Yi-Hsiang Hsu, Laura M Yerges-Armstrong, Wen-Chi Chou et al.
Nature communications, Journal article 2017
Journal article

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
M. C. Zillikens, S. Demissie, Y. H. Hsu, L. M. Yerges-Armstrong, W. C. Chou et al.
Nature Communications, Journal article 2017
Journal article

Showing 1 - 10 of 93

2018

Hyperandrogenism and insulin resistance contribute to hepatic steatosis and inflammation in female rat liver.
Yuehui Zhang, Fanci Meng, Xiaoyan Sun, Xue Sun, Min Hu et al.
Oncotarget, Journal article 2018
Journal article

Hyperandrogenism and insulin resistance contribute to hepatic steatosis and inflammation in female rat liver.
Yuehui Zhang, Fanci Meng, Xiaoyan Sun, Xue Sun, Min Hu et al.
Oncotarget, Journal article 2018
Journal article

Deficiency of liver-derived insulin-like growth factor-I (IGF-I) does not interfere with the skin wound healing rate
I. R. Botusan, X. Zheng, S. Narayanan, J. Grünler, V. G. Sunkari et al.
PLoS ONE, Journal article 2018
Journal article

Body weight homeostat that regulates fat mass independently of leptin in rats and mice.
John-Olov Jansson, Vilborg Palsdottir, Daniel Hägg, Erik Schéle, Suzanne L. Dickson et al.
Proceedings of the National Academy of Sciences of the United States of America, Journal article 2018
Journal article

2017

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
Mariaelisa Graff, Robert A Scott, Anne E Justice, Kristin L Young, Mary F Feitosa et al.
PLoS genetics, Journal article 2017
Journal article

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
M Carola Zillikens, Serkalem Demissie, Yi-Hsiang Hsu, Laura M Yerges-Armstrong, Wen-Chi Chou et al.
Nature communications, Journal article 2017
Journal article

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
M. C. Zillikens, S. Demissie, Y. H. Hsu, L. M. Yerges-Armstrong, W. C. Chou et al.
Nature Communications, Journal article 2017
Journal article

Showing 1 - 10 of 93

Page Manager: Julia Kisch|Last update: 5/6/2015
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