John-Olov Jansson

Seniorforskare

Sektionen för

fysiologi

Telefon

031-786 35 26

0739-01 11 22

E-post

john-olov.jansson@neuro.gu.se

Besöksadress

Medicinaregatan 11-13

41390 Göteborg

Postadress

Box 432

40530 Göteborg

Om John-Olov Jansson

Forskargrupp

Gravitostatgruppens hemsida

Undervisning

Professor Jansson är sedan många år engagerad i endokrinologiundervisningen (läran om hormoner, dvs signalsubstanser i blodet) för medicinstudenter och apotekarstudenter. J-O Jansson är också sedan 2009 kursledare för Biomedicinsk Fördjupningskurs (BF2), en kurs som han byggt upp frångrunden. Kursen syftar till att öka medicinstudenters förståelse för forskning.

Forskningsintressen

1. Gravitostaten - en homeostatistisk mechanism för att hålla kroppsvikt och fettmassa konstant.

Beskrivs på Gravitostatgruppens hemsida.

2. Interleukin-6 i hjärnan minskar fetma hos friska individer.

Vi har sedan början av 2000-talet studerat effekter immunsystemet (framför allt immunmodulatorerna interleukin-6 (IL-6) och IL-1) på mängden kroppsfett. Vi var de första att påvisa att friska möss med IL-6 knockout blev feta (Wallenius V et al 2002 Nat Med 8:75-79, citerad mer än 1300 gånger). Vi har ocksåvisat att I-1 betydelsen av IL-6 och IL-1 i hjärnan för mediering av den antifetma effekt som utövas av glukagon-lik peptid-1 (GLP-1) analoger. Intresset för detta projekt är stort eftersom GLP-1 analoger som exendin-4 (Byetta) och liraglutid (Victoza och Saxenda), i princip är de enda mono-läkemedlen mot fetma som finns på marknaden.

Pågående forskning / projekt

På senare år har vår forskning f a inriktats på studier av gravitostaten.

Publikationer

Osteoblast-lineage cells regulate metabolism and fat
mass

Daniel Hägg, Per-Anders Jansson, Jakob Bellman, John-Olov Jansson, Claes Ohlsson
Current Opinion in Endocrine and Metabolic Research - 2023
The dual hypothesis of homeostatic body weight regulation, including gravity-dependent and leptin-dependent
actions.

John-Olov Jansson, Fredrik Anesten, Daniel Hägg, Jovana Zlatowic, Suzanne L. Dickson, Per-Anders Jansson, Erik Schéle, Jakob Bellman, Claes Ohlsson
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 2023
Reduction of body weight by increased loading is associated with activation of norepinephrine neurones in the medial nucleus of the solitary
tract.

Jovana Zlatkovic, Adrià Dalmau Gasull, Daniel Hägg, Ferran Font Gironès, Jakob Bellman, Björn Meister, Vilborg Palsdottir, Johan Ruud, Claes Ohlsson, Suzanne L. Dickson, Fredrik Anesten, John-Olov Jansson
Journal of neuroendocrinology - 2023
Testosterone reduces metabolic brown fat activity in male
mice

Marta Lantero Rodriguez, M. Schilperoort, Inger Johansson, Elin Svedlund Eriksson, Vilborg Palsdottir, J. Kroon, Marcus Henricsson, S. Kooijman, Mia Ericson, Jan Borén, Claes Ohlsson, John-Olov Jansson, Malin Levin, P. C. N. Rensen, Åsa Tivesten
Journal of Endocrinology - 2021
The gravitostat protects diet-induced obese rats against fat accumulation and weight
gain

Tina Bake, Fiona Peris-Sampedro, Zita Wáczek, Claes Ohlsson, Vilborg Palsdottir, John-Olov Jansson, Suzanne L. Dickson
Journal of Neuroendocrinology - 2021
Revisiting the critical weight hypothesis for regulation of pubertal timing in
boys.

Maria Bygdell, Jenny Kindblom, John-Olov Jansson, Claes Ohlsson
The American journal of clinical nutrition - 2021
A Body Weight Sensor Regulates Prepubertal Growth via the Somatotropic Axis in Male
Rats

John-Olov Jansson, Adria Dalmau Gasull, Erik Schele, Suzanne L. Dickson, Vilborg Palsdottir, Anders Palmquist, Ferran Font Gironès, Jakob Bellman, Fredrik Anesten, Daniel Hägg, Claes Ohlsson
Endocrinology - 2021
The gravitostat theory: More data
needed

Claes Ohlsson, John-Olov Jansson
EClinicalMedicine - 2020
Increased weight loading reduces body weight and body fat in obese subjects – A proof of concept randomized clinical
trial

Claes Ohlsson, Edwin Gidestrand, Jakob Bellman, Christel Larsson, Vilborg Palsdottir, Daniel Hägg, Per-Anders Jansson, John-Olov Jansson
EClinicalMedicine - 2020
Spleen proteomics data from high fat diet fed
mice.

Sara L Svahn, Bagmi Pattanaik, Louise Grahnemo, Saray Gutiérrez, Intawat Nookaew, John-Olov Jansson, Maria E Johansson
Data in brief - 2020
Dietary Polyunsaturated Fatty Acids Promote Neutrophil Accumulation in the Spleen by Altering Chemotaxis and Delaying Cell
Death

Sara L Svahn, Saray Gutiérrez, Marcus A Ulleryd, I. Nookaew, Veronica Osla, Fredrik Beckman, Staffan Nilsson, Anna Karlsson, John-Olov Jansson, Maria E Johansson
Infection and Immunity - 2019
Interleukin-6 in the central amygdala is bioactive and co-localised with glucagon-like peptide-1
receptor

Fredrik Anesten, Adria Dalmau Gasull, Jennifer E. Richard, Imre Farkas, Devesh Mishra, Lilly Taing, F. Zhang, Matti Poutanen, Vilborg Palsdottir, Z. Liposits, Karolina P Skibicka, John-Olov Jansson
Journal of Neuroendocrinology - 2019
Glucagon-Like Peptide-1-, but not Growth and Differentiation Factor 15-, Receptor Activation Increases the Number of Interleukin-6-Expressing Cells in the External Lateral Parabrachial
Nucleus

Fredrik Anesten, Devesh Mishra, Adria Dalmau Gasull, Linda Engström-Ruud, Jakob Bellman, Vilborg Palsdottir, F Zhang, S. Trapp, Karolina P Skibicka, Matti Poutanen, John-Olov Jansson
Neuroendocrinology - 2019
Interactions Between the Gravitostat and the Fibroblast Growth Factor System for the Regulation of Body
Weight

Vilborg Palsdottir, Sara H Windahl, Daniel Hägg, Hanna Keantar, Jakob Bellman, A. Buchanan, T. J. Vaughan, Daniel Lindén, John-Olov Jansson, Claes Ohlsson
Endocrinology - 2019
Disentangling the genetics of lean
mass

D. Karasik, M. C. Zillikens, Y. H. Hsu, A. Aghdassi, K. Akesson, N. Amin, I. Barroso, D. A. Bennett, L. Bertram, M. Bochud, I. B. Borecki, L. Broer, A. S. Buchman, L. Byberg, H. Campbell, N. Campos-Obando, J. A. Cauley, P. M. Cawthon, J. C. Chambers, Z. Chen, N. H. Cho, H. J. Choi, W. C. Chou, S. R. Cummings, Lcpgm de Groot, P. L. De Jager, I. Demuth, L. Diatchenko, M. J. Econs, G. Eiriksdottir, A. W. Enneman, Joel Eriksson, J. G. Eriksson, K. Estrada, D. S. Evans, M. F. Feitosa, M. Fu, C. Gieger, H. Grallert, V. Gudnason, L. J. Lenore, C. Hayward, A. Hofman, G. Homuth, K. M. Huffman, L. B. Husted, T. Illig, E. Ingelsson, T. Ittermann, John-Olov Jansson, T. Johnson, R. Biffar, J. M. Jordan, A. Jula, M. Karlsson, K. T. Khaw, T. O. Kilpelainen, N. Klopp, J. S. L. Kloth, D. L. Koller, J. S. Kooner, W. E. Kraus, S. Kritchevsky, Z. Kutalik, T. Kuulasmaa, J. Kuusisto, M. Laakso, J. Lahti, T. Lang, B. L. Langdahl, M. M. Lerch, J. R. Lewis, C. Lill, L. Lind, C. Lindgren, Y. M. Liu, G. Livshits, O. Ljunggren, R. J. F. Loos, Mattias Lorentzon, J. Luan, R. N. Luben, I. Malkin, F. E. McGuigan, C. Medina-Gomez, T. Meitinger, H. Melhus, Dan Mellström, K. Michaelsson, B. D. Mitchell, A. P. Morris, L. Mosekilde, Maria Nethander, A. B. Newman, J. R. O'Connell, B. A. Oostra, E. S. Orwoll, A. Palotie, M. Peacock, M. Perola, A. Peters, R. L. Prince, B. M. Psaty, K. Raikkonen, S. H. Ralston, S. Ripatti, F. Rivadeneira, J. A. Robbins, J. I. Rotter, I. Rudan, V. Salomaa, S. Satterfield, S. Schipf, C. S. Shin, A. V. Smith, S. B. Smith, N. Soranzo, T. D. Spector, A. Stancakova, K. Stefansson, E. Steinhagen-Thiessen, L. Stolk, E. A. Streeten, U. Styrkarsdottir, K. M. A. Swart, P. Thompson, C. A. Thomson, G. Thorleifsson, U. Thorsteinsdottir, E. Tikkanen, G. J. Tranah, A. G. Uitterlinden, C. M. van Duijn, N. M. van Schoor, L. Vandenput, P. Vollenweider, H. Volzke, J. Wactawski-Wende, M. Walker, N. J. Wareham, D. Waterworth, M. N. Weedon, H. E. Wichmann, E. Widen, F. M. K. Williams, J. F. Wilson, N. C. Wright, L. M. Yerges-Armstrong, L. Yu, W. H. Zhang, J. H. Zhao, Y. H. Zhou, C. M. Nielson, T. B. Harris, S. Demissie, D. P. Kiel, Claes Ohlsson
American Journal of Clinical Nutrition - 2019
The Gravitostat Regulates Fat Mass in Obese Male Mice While Leptin Regulates Fat Mass in Lean Male
Mice

Claes Ohlsson, Daniel Hägg, Fredrik Hammarhjelm, Adria Gasull, Jakob Bellman, Sara H Windahl, Vilborg Palsdottir, John-Olov Jansson
Endocrinology - 2018
Reply to Lund: Where does the gravitostat fit
in?

Claes Ohlsson, John-Olov Jansson
Proceedings of the National Academy of Sciences of the United States of America - 2018
Hyperandrogenism and insulin resistance contribute to hepatic steatosis and inflammation in female rat
liver.

Yuehui Zhang, Fanci Meng, Xiaoyan Sun, Xue Sun, Min Hu, Peng Cui, Edvin Vestin, Xin Li, Wei Li, Xiao-Ke Wu, John-Olov Jansson, Linus Ruijin Shao, Håkan Billig
Oncotarget - 2018
Body weight homeostat that regulates fat mass independently of leptin in rats and
mice.

John-Olov Jansson, Vilborg Palsdottir, Daniel Hägg, Erik Schéle, Suzanne L. Dickson, Fredrik Anesten, Tina Bake, Mikael Montelius, Jakob Bellman, Maria E I Johansson, Roger D Cone, Daniel J Drucker, Jianyao Wu, Biljana Aleksic, Anna E Törnqvist, Klara Sjögren, Jan-Åke Gustafsson, Sara H Windahl, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2018
Deficiency of liver-derived insulin-like growth factor-I (IGF-I) does not interfere with the skin wound healing
rate

I. R. Botusan, X. Zheng, S. Narayanan, J. Grünler, V. G. Sunkari, F. S. Calissendorff, I. Ansurudeen, C. Illies, Johan Svensson, John-Olov Jansson, Claes Ohlsson, K. Brismar, S. B. Catrina
PLoS ONE - 2018
Functional interleukin-6 receptor- is located in tanycytes at the base of the third
ventricle

Fredrik Anesten, Cristiano Santos, Edwin Gidestrand, Erik Schéle, Vilborg Palsdottir, Teodor Swedung-Wettervik, B. Meister, Karolina P Skibicka, John-Olov Jansson
Journal of Neuroendocrinology - 2017
Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male
mice.

Claes Ohlsson, Ann Hammarstedt, Liesbeth Vandenput, Niina Saarinen, Henrik Ryberg, Sara H Windahl, Helen H. Farman, John-Olov Jansson, Sofia Movérare-Skrtic, Ulf Smith, Fu-Ping Zhang, Matti Poutanen, Shahram Hedjazifar, Klara Sjögren
American journal of physiology. Endocrinology and metabolism - 2017
BMP4 Gene Therapy in Mature Mice Reduces BAT Activation but Protects from Obesity by Browning Subcutaneous Adipose
Tissue.

Jenny M Hoffmann, John Grünberg, Christopher Church, Ivet Elias, Vilborg Palsdottir, John-Olov Jansson, Fatima Bosch, Ann Hammarstedt, Shahram Hedjazifar, Ulf Smith
Cell reports - 2017
Large meta-analysis of genome-wide association studies identifies five loci for lean body
mass

M. C. Zillikens, S. Demissie, Y. H. Hsu, L. M. Yerges-Armstrong, W. C. Chou, L. Stolk, G. Livshits, L. Broer, T. Johnson, D. L. Koller, Z. Kutalik, J. Luan, I. Malkin, J. S. Ried, A. V. Smith, G. Thorleifsson, Liesbeth Vandenput, J. H. Zhao, W. H. Zhang, A. Aghdassi, K. Akesson, N. Amin, L. J. Baier, I. Barroso, D. A. Bennett, L. Bertram, R. Biffar, M. Bochud, M. Boehnke, I. B. Borecki, A. S. Buchman, L. Byberg, H. Campbell, N. C. Obanda, J. A. Cauley, P. M. Cawthon, H. Cederberg, Z. Chen, N. H. Cho, H. J. Choi, M. Claussnitzer, F. Collins, S. R. Cummings, P. L. De Jager, I. Demuth, R. A. M. Dhonukshe-Rutten, L. Diatchenko, G. Eiriksdottir, A. W. Enneman, M. Erdos, J. G. Eriksson, Joel Eriksson, K. Estrada, D. S. Evans, M. F. Feitosa, M. Fu, M. Garcia, C. Gieger, T. Girke, N. L. Glazer, H. Grallert, J. Grewal, B. G. Han, R. L. Hanson, C. Hayward, A. Hofman, E. P. Hoffman, G. Homuth, W. C. Hsueh, M. J. Hubal, A. Hubbard, K. M. Huffman, L. B. Husted, T. Illig, E. Ingelsson, T. Ittermann, John-Olov Jansson, J. M. Jordan, A. Jula, M. Karlsson, K. T. Khaw, T. O. Kilpainen, N. Klopp, J. S. L. Kloth, H. A. Koistinen, W. E. Kraus, S. Kritchevsky, T. Kuulasmaa, J. Kuusisto, M. Laakso, J. Lahti, T. Lang, B. L. Langdahl, L. J. Launer, J. Y. Lee, M. M. Lerch, J. R. Lewis, L. Lind, C. Lindgren, Y. M. Liu, T. Liu, Y. F. Liu, O. Ljunggren, Mattias Lorentzon, R. N. Luben, W. Maixner, F. E. McGuigan, C. Medina-Gomez, T. Meitinger, H. Melhus, Dan Mellström, S. Melov, K. Michaelsson, B. D. Mitchell, A. P. Morris, L. Mosekilde, A. Newman, C. M. Nielson, J. R. O'Connell, B. A. Oostra, E. S. Orwoll, A. Palotie, S. Parker, M. Peacock, M. Perola, A. Peters, O. Polasek, R. L. Prince, K. Raikkonen, S. H. Ralston, S. Ripatti, J. A. Robbins, J. I. Rotter, I. Rudan, V. Salomaa, S. Satterfield, E. E. Schadt, S. Schipf, L. Scott, J. Sehmi, J. Shen, C. S. Shin, G. Sigurdsson, S. Smith, N. Soranzo, A. Stancakova, E. Steinhagen-Thiessen, E. A. Streeten, U. Styrkarsdottir, K. M. A. Swart, S. T. Tan, M. A. Tarnopolsky, P. Thompson, C. A. Thomson, U. Thorsteinsdottir, E. Tikkanen, G. J. Tranah, J. Tuomilehto, N. M. van Schoor, A. Verma, P. Vollenweider, H. Volzke, J. Wactawski-Wende, M. Walker, M. N. Weedon, R. Welch, H. E. Wichman, E. Widen, F. M. K. Williams, J. F. Wilson, N. C. Wright, W. J. Xie, L. Yu, Y. H. Zhou, J. C. Chambers, A. Doring, C. M. van Duijn, M. J. Econs, V. Gudnason, J. S. Kooner, B. M. Psaty, T. D. Spector, K. Stefansson, F. Rivadeneira, A. G. Uitterlinden, N. J. Wareham, V. Ossowski, D. Waterworth, R. J. F. Loos, D. Karasik, T. B. Harris, Claes Ohlsson, D. P. Kiel, V. P. Nada
Nature Communications - 2017
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity
traits

A. E. Justice, T. W. Winkler, M. F. Feitosa, M. Graff, V. A. Fisher, K. Young, L. Barata, X. Deng, J. Czajkowski, D. Hadley, J. S. Ngwa, T. S. Ahluwalia, A. Y. Chu, N. L. Heard-Costa, E. Lim, J. Perez, J. D. Eicher, Z. Kutalik, L. Xue, A. Mahajan, F. Renstrom, J. Wu, Q. B. Qi, S. Ahmad, T. Alfred, N. Amin, L. F. Bielak, A. Bonnefond, J. Bragg, G. Cadby, M. Chittani, S. Coggeshall, T. Corre, N. Direk, Joel Eriksson, K. Fischer, M. Gorski, M. N. Harder, M. Horikoshi, T. Huang, J. E. Huffman, A. U. Jackson, J. M. Justesen, S. Kanoni, L. Kinnunen, M. E. Kleber, P. Komulainen, M. Kumari, U. Lim, J. Luan, L. P. Lyytikainen, M. Mangino, A. Manichaikul, J. Marten, R. P. S. Middelberg, M. Mueller-Nurasyid, P. Navarro, L. Perusse, N. Pervjakova, C. Sarti, A. V. Smith, J. A. Smith, A. Stancakova, R. J. Strawbridge, H. M. Stringham, Y. J. Sung, T. Tanaka, A. Teumer, S. Trompet, S. W. van der Laan, P. J. van der Most, J. V. Van Vliet-Ostaptchouk, S. L. Vedantam, N. Verweij, J. M. Vink, V. Vitart, Y. Wu, L. Yengo, W. H. Zhang, J. H. Zhao, M. E. Zimmermann, N. Zubair, G. R. Abecasis, L. S. Adair, S. Afaq, U. Afzal, S. J. L. Bakker, T. M. Bartz, J. Beilby, R. N. Bergman, S. Bergmann, R. Biffar, J. Blangero, E. Boerwinkle, L. L. Bonnycastle, E. Bottinger, D. Braga, B. M. Buckley, S. Buyske, H. Campbell, J. C. Chambers, F. S. Collins, J. E. Curran, G. J. de Borst, A. J. M. de Craen, E. J. C. de Geus, G. Dedoussis, G. E. Delgado, H. M. den Ruijter, G. Eiriksdottir, Anna-Lena Eriksson, T. Esko, J. D. Faul, I. Ford, T. Forrester, K. Gertow, B. Gigante, N. Glorioso, J. Gong, H. Grallert, T. B. Grammer, N. Grarup, S. Haitjema, G. Hallmans, A. Hamsten, T. Hansen, T. B. Harris, C. A. Hartman, M. Hassinen, N. D. Hastie, A. C. Heath, D. Hernandez, L. Hindorff, L. J. Hocking, M. Hollensted, O. L. Holmen, G. Homuth, J. J. Hottenga, J. Huang, J. Hung, N. Hutri-Kahonen, E. Ingelsson, A. L. James, John-Olov Jansson, M. R. Jarvelin, M. A. Jhun, M. E. Jorgensen, M. Juonala, M. Kahonen, M. Karlsson, H. A. Koistinen, I. Kolcic, G. Kolovou, C. Kooperberg, B. K. Kramer, J. Kuusisto, K. Kvaloy, T. A. Lakka, C. Langenberg, L. J. Launer, K. Leander, N. R. Lee, L. Lind, C. M. Lindgren, A. Linneberg, S. Lobbens, M. Loh, Mattias Lorentzon, R. Luben, G. Lubke, A. Ludolph-Donislawski, S. Lupoli, P. A. F. Madden, R. Mannikko, P. Marques-Vidal, N. G. Martin, C. A. McKenzie, B. McKnight, Dan Mellström, C. Menni, G. W. Montgomery, A. W. Musk, N. Narisu, M. Nauck, I. M. Nolte, A. J. Oldehinkel, M. Olden, K. K. Ong, S. Padmanabhan, P. A. Peyser, C. Pisinger, D. J. Porteous, O. T. Raitakari, T. Rankinen, D. C. Rao, L. J. Rasmussen-Torvik, R. Rawal, T. Rice, P. M. Ridker, L. M. Rose, S. A. Bien, I. Rudan, S. Sanna, M. A. Sarzynski, N. Sattar, K. Savonen, D. Schlessinger, S. Scholtens, C. Schurmann, R. A. Scott, B. Sennblad, M. A. Siemelink, G. Silbernagel, P. E. Slagboom, H. Snieder, J. A. Staessen, D. J. Stott, M. A. Swertz, A. J. Swift, K. D. Taylor, B. O. Tayo, B. Thorand, D. Thuillier, J. Tuomilehto, A. G. Uitterlinden, Liesbeth Vandenput, M. C. Vohl, H. Volzke, J. M. Vonk, G. Waeber, M. Waldenberger, R. G. J. Westendorp, S. Wild, G. Willemsen, B. H. R. Wolffenbuttel, A. Wong, A. F. Wright, W. Zhao, M. C. Zillikens, D. Baldassarre, B. Balkau, S. Bandinelli, C. A. Boger, D. I. Boomsma, C. Bouchard, M. Bruinenberg, D. I. Chasman, Y. D. I. Chen, P. S. Chines, R. S. Cooper, F. Cucca, D. Cusi, U. de Faire, L. Ferrucci, P. W. Franks, P. Froguel, P. Gordon-Larsen, H. J. Grabe, V. Gudnason, C. A. Haiman, C. Hayward, K. Hveem, A. D. Johnson, W. Jukema, S. L. R. Kardia, M. Kivimaki, J. S. Kooner, D. Kuh, M. Laakso, T. Lehtimaki, L. Le Marchand, W. Marz, M. I. McCarthy, A. Metspalu, A. P. Morris, Claes Ohlsson, L. J. Palmer, G. Pasterkamp, O. Pedersen, A. Peters, U. Peters, O. Polasek, B. M. Psaty, L. Qi, R. Rauramaa, B. H. Smith, T. I. A. Sorensen, K. Strauch, H. Tiemeier, E. Tremoli, P. Van der Harst, H. Vestergaard, P. Vollenweider, N. J. Wareham, D. R. Weir, J. B. Whitfield, J. F. Wilson, J. Tyrrell, T. M. Frayling, I. Barroso, M. Boehnke, P. Deloukas, C. S. Fox, J. N. Hirschhorn, D. J. Hunter, T. D. Spector, D. P. Strachan, C. M. van Duijn, I. M. Heid, K. L. Mohlke, J. Marchini, R. J. F. Loos, T. O. Kilpelainen, C. T. Liu, I. B. Borecki, K. E. North, L. A. Cupples
Nature Communications - 2017
Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452
adults

M. Graff, R. A. Scott, A. E. Justice, K. L. Young, M. F. Feitosa, L. Barata, T. W. Winkler, A. Y. Chu, A. Mahajan, D. Hadley, L. T. Xue, T. Workalemahu, N. L. Heard-Costa, M. den Hoed, T. S. Ahluwalia, Q. B. Qi, J. S. Ngwa, F. Renstrom, L. Quaye, J. D. Eicher, J. E. Hayes, M. Cornelis, Z. Kutalik, E. Lim, J. Luan, J. E. Huffman, W. H. Zhang, W. Zhao, P. J. Griffin, T. Haller, S. Ahmad, P. M. Marques-Vidal, S. Bien, L. Yengo, A. Teumer, A. V. Smith, M. Kumari, M. N. Harder, J. M. Justesen, M. E. Kleber, M. Hollensted, K. Lohman, N. V. Rivera, J. B. Whitfield, J. H. Zhao, H. M. Stringham, L. P. Lyytikainen, C. Huppertz, G. Willemsen, W. J. Peyrot, Y. Wu, K. Kristiansson, A. Demirkan, M. Fornage, M. Hassinen, L. F. Bielak, G. Cadby, T. Tanaka, R. Magl, P. J. Van der Most, A. U. Jackson, J. L. Bragg-Gresham, V. Vitart, J. Marten, P. Navarro, C. Bellis, D. Pasko, A. Johansson, S. Snitker, Y. C. Cheng, Joel Eriksson, U. Lim, M. Aadahl, L. S. Adair, N. Amin, B. Balkau, J. Auvinen, J. Beilby, R. N. Bergman, S. Bergmann, A. G. Bertoni, J. Blangero, A. Bonnefond, L. L. Bonnycastle, J. B. Borja, S. Brage, F. Busonero, S. Buyske, H. Campbell, P. S. Chines, F. S. Collins, T. Corre, G. D. Smith, G. E. Delgado, N. Dueker, M. Dorr, T. Ebeling, G. Eiriksdottir, T. Esko, J. D. Faul, M. Fu, K. Faerch, C. Gieger, S. Glaser, J. Gong, P. Gordon-Larsen, H. Grallert, T. B. Grammer, N. Grarup, G. van Grootheest, K. Harald, N. D. Hastie, A. S. Havulinna, D. Hernandez, L. Hindorff, L. J. Hocking, O. L. Holmens, C. Holzapfel, J. J. Hottenga, J. Huang, T. Huang, J. Hui, C. Huth, N. Hutri-Kahonen, A. L. James, John-Olov Jansson, M. A. Jhun, M. Juonala, L. Kinnunen, H. A. Koistinen, I. Kolcic, P. Komulainen, J. Kuusisto, K. Kvaloy, M. Kahonen, T. A. Lakka, L. J. Launer, B. Lehne, C. M. Lindgren, Mattias Lorentzon, R. Luben, M. Marre, Y. Milaneschi, K. L. Monda, G. W. Montgomery, M. H. M. De Moor, A. Mulas, M. Muller-Nurasyid, A. W. Musk, R. Mannikko, S. Mannisto, N. Narisu, M. Nauck, J. A. Nettleton, I. M. Nolte, A. J. Oldehinkel, M. Olden, K. K. Ong, S. Padmanabhan, L. Paternoster, J. Perez, M. Perola, A. Peters, U. Peters, P. A. Peyser, I. Prokopenko, H. Puolijoki, O. T. Raitakari, T. Rankinen, L. J. Rasmussen-Torvik, R. Rawal, P. M. Ridker, L. M. Rose, I. Rudan, C. Sarti, M. A. Sarzynski, K. Savonen, W. R. Scott, S. Sanna, A. R. Shuldiner, S. Sidney, G. Silbernagel, B. H. Smith, J. A. Smith, H. Snieder, A. Stancakova, B. Sternfeld, A. J. Swift, T. Tammelin, S. T. Tan, B. Thorand, D. Thuillier, Liesbeth Vandenput, H. Vestergaard, J. V. van Vliet-Ostaptchouk, M. C. Vohl, U. Volker, G. Waeber, M. Walker, S. Wild, A. Wong, A. F. Wright, M. C. Zillikens, N. Zubair, C. A. Haiman, L. Lemarchand, U. Gyllensten, Claes Ohlsson, C. Ohlsson, A. Hofman, F. Rivadeneira, A. G. Uitterlinden, L. Perusse, J. F. Wilson, C. Hayward, O. Polasek, F. Cucca, K. Hveem, C. A. Hartman, A. Tonjes, S. Bandinelli, L. J. Palmer, S. L. R. Kardia, R. Rauramaa, T. I. A. Sorensen, J. Tuomilehto, V. Salomaa, Bwjh Penninx, E. J. C. de Geus, D. I. Boomsma, T. Lehtimaki, M. Mangino, M. Laakso, C. Bouchard, N. G. Martin, D. Kuh, Y. M. Liu, A. Linneberg, W. Marz, K. Strauch, M. Kivimaki, T. B. Harris, V. Gudnason, H. Volzke, L. Qi, M. R. Jarvelin, J. C. Chambers, J. S. Kooner, P. Froguel, C. Kooperberg, P. Vollenweider, G. Hallmans, T. Hansen, O. Pedersen, A. Metspalu, N. J. Wareham, C. Langenberg, D. R. Weir, D. J. Porteous, E. Boerwinkle, D. I. Chasman, G. R. Abecasis, I. Barroso, M. I. McCarthy, T. M. Frayling, J. R. O'Connell, C. M. van Duijn, M. Boehnke, I. M. Heid, K. L. Mohlke, D. P. Strachan, C. S. Fox, C. T. Liu, J. N. Hirschhorn, R. J. Klein, A. D. Johnson, I. B. Borecki, P. W. Franks, K. E. North, L. A. Cupples, R. J. F. Loos, T. O. Kilpelainen, Charge Consortium; EPIC-InterAct Consortium; PAGE Consortium Charge Consortium; EPIC-InterAct Consortium; PAGE Consortium
PLoS Genet - 2017
Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body
mass.

M Carola Zillikens, Serkalem Demissie, Yi-Hsiang Hsu, Laura M Yerges-Armstrong, Wen-Chi Chou, Lisette Stolk, Gregory Livshits, Linda Broer, Toby Johnson, Daniel L Koller, Zoltán Kutalik, Jian'an Luan, Ida Malkin, Janina S Ried, Albert V Smith, Gudmar Thorleifsson, Liesbeth Vandenput, Jing Hua Zhao, Weihua Zhang, Ali Aghdassi, Kristina Åkesson, Najaf Amin, Leslie J Baier, Inês Barroso, David A Bennett, Lars Bertram, Rainer Biffar, Murielle Bochud, Michael Boehnke, Ingrid B Borecki, Aron S Buchman, Liisa Byberg, Harry Campbell, Natalia Campos Obanda, Jane A Cauley, Peggy M Cawthon, Henna Cederberg, Zhao Chen, Nam H Cho, Hyung Jin Choi, Melina Claussnitzer, Francis Collins, Steven R Cummings, Philip L De Jager, Ilja Demuth, Rosalie A M Dhonukshe-Rutten, Luda Diatchenko, Gudny Eiriksdottir, Anke W Enneman, Mike Erdos, Johan G Eriksson, Joel Eriksson, Karol Estrada, Daniel S Evans, Mary F Feitosa, Mao Fu, Melissa Garcia, Christian Gieger, Thomas Girke, Nicole L Glazer, Harald Grallert, Jagvir Grewal, Bok-Ghee Han, Robert L Hanson, Caroline Hayward, Albert Hofman, Eric P Hoffman, Georg Homuth, Wen-Chi Hsueh, Monica J Hubal, Alan Hubbard, Kim M Huffman, Lise B Husted, Thomas Illig, Erik Ingelsson, Till Ittermann, John-Olov Jansson, Joanne M Jordan, Antti Jula, Magnus Karlsson, Kay-Tee Khaw, Tuomas O Kilpeläinen, Norman Klopp, Jacqueline S L Kloth, Heikki A Koistinen, William E Kraus, Stephen Kritchevsky, Teemu Kuulasmaa, Johanna Kuusisto, Markku Laakso, Jari Lahti, Thomas Lang, Bente L Langdahl, Lenore J Launer, Jong-Young Lee, Markus M Lerch, Joshua R Lewis, Lars Lind, Cecilia Lindgren, Yongmei Liu, Tian Liu, Youfang Liu, Östen Ljunggren, Mattias Lorentzon, Robert N Luben, William Maixner, Fiona E McGuigan, Carolina Medina-Gomez, Thomas Meitinger, Håkan Melhus, Dan Mellström, Simon Melov, Karl Michaëlsson, Braxton D Mitchell, Andrew P Morris, Leif Mosekilde, Anne Newman, Carrie M Nielson, Jeffrey R O'Connell, Ben A Oostra, Eric S Orwoll, Aarno Palotie, Stephen C J Parker, Munro Peacock, Markus Perola, Annette Peters, Ozren Polasek, Richard L Prince, Katri Räikkönen, Stuart H Ralston, Samuli Ripatti, John A Robbins, Jerome I Rotter, Igor Rudan, Veikko Salomaa, Suzanne Satterfield, Eric E Schadt, Sabine Schipf, Laura Scott, Joban Sehmi, Jian Shen, Chan Soo Shin, Gunnar Sigurdsson, Shad Smith, Nicole Soranzo, Alena Stančáková, Elisabeth Steinhagen-Thiessen, Elizabeth A Streeten, Unnur Styrkarsdottir, Karin M A Swart, Sian-Tsung Tan, Mark A Tarnopolsky, Patricia Thompson, Cynthia A Thomson, Unnur Thorsteinsdottir, Emmi Tikkanen, Gregory J Tranah, Jaakko Tuomilehto, Natasja M van Schoor, Arjun Verma, Peter Vollenweider, Henry Völzke, Jean Wactawski-Wende, Mark Walker, Michael N Weedon, Ryan Welch, H-Erich Wichmann, Elisabeth Widen, Frances M K Williams, James F Wilson, Nicole C Wright, Weijia Xie, Lei Yu, Yanhua Zhou, John C Chambers, Angela Döring, Cornelia M van Duijn, Michael J Econs, Vilmundur Gudnason, Jaspal S Kooner, Bruce M Psaty, Timothy D Spector, Kari Stefansson, Fernando Rivadeneira, André G Uitterlinden, Nicholas J Wareham, Vicky Ossowski, Dawn Waterworth, Ruth J F Loos, David Karasik, Tamara B Harris, Claes Ohlsson, Douglas P Kiel
Nature communications - 2017
Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452
adults.

Mariaelisa Graff, Robert A Scott, Anne E Justice, Kristin L Young, Mary F Feitosa, Llilda Barata, Thomas W Winkler, Audrey Y Chu, Anubha Mahajan, David Hadley, Luting Xue, Tsegaselassie Workalemahu, Nancy L Heard-Costa, Marcel den Hoed, Tarunveer S Ahluwalia, Qibin Qi, Julius S Ngwa, Frida Renström, Lydia Quaye, John D Eicher, James E Hayes, Marilyn Cornelis, Zoltan Kutalik, Elise Lim, Jian'an Luan, Jennifer E Huffman, Weihua Zhang, Wei Zhao, Paula J Griffin, Toomas Haller, Shafqat Ahmad, Pedro M Marques-Vidal, Stephanie Bien, Loic Yengo, Alexander Teumer, Albert Vernon Smith, Meena Kumari, Marie Neergaard Harder, Johanne Marie Justesen, Marcus E Kleber, Mette Hollensted, Kurt Lohman, Natalia V Rivera, John B Whitfield, Jing Hua Zhao, Heather M Stringham, Leo-Pekka Lyytikäinen, Charlotte Huppertz, Gonneke Willemsen, Wouter J Peyrot, Ying Wu, Kati Kristiansson, Ayse Demirkan, Myriam Fornage, Maija Hassinen, Lawrence F Bielak, Gemma Cadby, Toshiko Tanaka, Reedik Mägi, Peter J van der Most, Anne U Jackson, Jennifer L Bragg-Gresham, Veronique Vitart, Jonathan Marten, Pau Navarro, Claire Bellis, Dorota Pasko, Åsa Johansson, Søren Snitker, Yu-Ching Cheng, Joel Eriksson, Unhee Lim, Mette Aadahl, Linda S Adair, Najaf Amin, Beverley Balkau, Juha Auvinen, John Beilby, Richard N Bergman, Sven Bergmann, Alain G Bertoni, John Blangero, Amélie Bonnefond, Lori L Bonnycastle, Judith B Borja, Søren Brage, Fabio Busonero, Steve Buyske, Harry Campbell, Peter S Chines, Francis S Collins, Tanguy Corre, George Davey Smith, Graciela E Delgado, Nicole Dueker, Marcus Dörr, Tapani Ebeling, Gudny Eiriksdottir, Tõnu Esko, Jessica D Faul, Mao Fu, Kristine Færch, Christian Gieger, Sven Gläser, Jian Gong, Penny Gordon-Larsen, Harald Grallert, Tanja B Grammer, Niels Grarup, Gerard van Grootheest, Kennet Harald, Nicholas D Hastie, Aki S Havulinna, Dena Hernandez, Lucia Hindorff, Lynne J Hocking, Oddgeir L Holmens, Christina Holzapfel, Jouke Jan Hottenga, Jie Huang, Tao Huang, Jennie Hui, Cornelia Huth, Nina Hutri-Kähönen, Alan L James, John-Olov Jansson, Min A Jhun, Markus Juonala, Leena Kinnunen, Heikki A Koistinen, Ivana Kolcic, Pirjo Komulainen, Johanna Kuusisto, Kirsti Kvaløy, Mika Kähönen, Timo A Lakka, Lenore J Launer, Benjamin Lehne, Cecilia M Lindgren, Mattias Lorentzon, Robert Luben, Michel Marre, Yuri Milaneschi, Keri L Monda, Grant W Montgomery, Marleen H M De Moor, Antonella Mulas, Martina Müller-Nurasyid, A W Musk, Reija Männikkö, Satu Männistö, Narisu Narisu, Matthias Nauck, Jennifer A Nettleton, Ilja M Nolte, Albertine J Oldehinkel, Matthias Olden, Ken K Ong, Sandosh Padmanabhan, Lavinia Paternoster, Jeremiah Perez, Markus Perola, Annette Peters, Ulrike Peters, Patricia A Peyser, Inga Prokopenko, Hannu Puolijoki, Olli T Raitakari, Tuomo Rankinen, Laura J Rasmussen-Torvik, Rajesh Rawal, Paul M Ridker, Lynda M Rose, Igor Rudan, Cinzia Sarti, Mark A Sarzynski, Kai Savonen, William R Scott, Serena Sanna, Alan R Shuldiner, Steve Sidney, Günther Silbernagel, Blair H Smith, Jennifer A Smith, Harold Snieder, Alena Stančáková, Barbara Sternfeld, Amy J Swift, Tuija Tammelin, Sian-Tsung Tan, Barbara Thorand, Dorothée Thuillier, Liesbeth Vandenput, Henrik Vestergaard, Jana V van Vliet-Ostaptchouk, Marie-Claude Vohl, Uwe Völker, Gérard Waeber, Mark Walker, Sarah Wild, Andrew Wong, Alan F Wright, M Carola Zillikens, Niha Zubair, Christopher A Haiman, Loic Lemarchand, Ulf Gyllensten, Claes Ohlsson, Albert Hofman, Fernando Rivadeneira, André G Uitterlinden, Louis Pérusse, James F Wilson, Caroline Hayward, Ozren Polasek, Francesco Cucca, Kristian Hveem, Catharina A Hartman, Anke Tönjes, Stefania Bandinelli, Lyle J Palmer, Sharon L R Kardia, Rainer Rauramaa, Thorkild I A Sørensen, Jaakko Tuomilehto, Veikko Salomaa, Brenda W J H Penninx, Eco J C de Geus, Dorret I Boomsma, Terho Lehtimäki, Massimo Mangino, Markku Laakso, Claude Bouchard, Nicholas G Martin, Diana Kuh, Yongmei Liu, Allan Linneberg, Winfried März, Konstantin Strauch, Mika Kivimäki, Tamara B Harris, Vilmundur Gudnason, Henry Völzke, Lu Qi, Marjo-Riitta Järvelin, John C Chambers, Jaspal S Kooner, Philippe Froguel, Charles Kooperberg, Peter Vollenweider, Göran Hallmans, Torben Hansen, Oluf Pedersen, Andres Metspalu, Nicholas J Wareham, Claudia Langenberg, David R Weir, David J Porteous, Eric Boerwinkle, Daniel I Chasman, Gonçalo R Abecasis, Inês Barroso, Mark I McCarthy, Timothy M Frayling, Jeffrey R O'Connell, Cornelia M van Duijn, Michael Boehnke, Iris M Heid, Karen L Mohlke, David P Strachan, Caroline S Fox, Ching-Ti Liu, Joel N Hirschhorn, Robert J Klein, Andrew D Johnson, Ingrid B Borecki, Paul W Franks, Kari E North, L Adrienne Cupples, Ruth J F Loos, Tuomas O Kilpeläinen
PLoS genetics - 2017
Dietary Omega-3 Fatty Acids Increase Survival and Decrease Bacterial Load in Mice Subjected to Staphylococcus aureus-Induced
Sepsis

Sara L Svahn, Marcus A Ulleryd, Louise Grahnemo, Marcus Ståhlman, Jan Borén, Staffan Nilsson, John-Olov Jansson, Maria E Johansson
Infection and Immunity - 2016
Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related
traits

A. Teumer, Q. Qi, Maria Nethander, H. Aschard, S. Bandinelli, M. Beekman, S. I. Berndt, M. Bidlingmaier, L. Broer, A. Cappola, G. P. Ceda, S. Chanock, M. H. Chen, T. C. Chen, Y. D. I. Chen, J. Chung, F. Del Greco Miglianico, Joel Eriksson, L. Ferrucci, N. Friedrich, C. Gnewuch, M. O. Goodarzi, N. Grarup, T. Guo, E. Hammer, R. B. Hayes, A. A. Hicks, A. Hofman, J. J. Houwing-Duistermaat, F. Hu, D. J. Hunter, L. L. Husemoen, A. Isaacs, K. B. Jacobs, J. A. M. J. L. Janssen, John-Olov Jansson, N. Jehmlich, S. Johnson, A. Juul, M. Karlsson, T. O. Kilpelainen, P. Kovacs, P. Kraft, C. Li, A. Linneberg, Y. Liu, R. J. F. Loos, Mattias Lorentzon, Y. Lu, M. Maggio, R. Magi, J. Meigs, Dan Mellström, M. Nauck, A. B. Newman, M. N. Pollak, P. P. Pramstaller, I. Prokopenko, B. M. Psaty, M. Reincke, E. B. Rimm, J. I. Rotter, A. Saint Pierre, C. Schurmann, S. Seshadri, Klara Sjögren, P. E. Slagboom, H. D. Strickler, M. Stumvoll, Y. Suh, Q. Sun, C. Zhang, Johan Svensson, T. Tanaka, A. Tare, A. Tönjes, H. W. Uh, C. M. Van Duijn, D. van Heemst, Liesbeth Vandenput, R. S. Vasan, U. Völker, Sara M. Willems, Claes Ohlsson, H. Wallaschofski, R. C. Kaplan
Aging Cell - 2016
Preproglucagon neurons in the hindbrain have IL-6 receptor-α and show Ca2+ influx in response to
IL-6

Fredrik Anesten, M. K. Holt, Erik Schéle, Vilborg Palsdottir, F. Reimann, F. M. Gribble, Cecilia Safari, Karolina P Skibicka, S. Trapp, John-Olov Jansson
American Journal of Physiology. Regulatory Integrative and Comparative Physiology - 2016
Female Mice Lacking Estrogen Receptor-alpha in Hypothalamic Proopiomelanocortin (POMC) Neurons Display Enhanced Estrogenic Response on Cortical Bone
Mass

Helen H. Farman, Sara H Windahl, Lars Westberg, H. Isaksson, Emil Egecioglu, Erik Schéle, Henrik Ryberg, John-Olov Jansson, J. Tuukkanen, A. Koskela, S. K. Xie, L. Hahner, J. Zehr, D. J. Clegg, Marie K Lagerquist, Claes Ohlsson
Endocrinology - 2016
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin
levels

Tuomas O. Kilpeläinen, Jayne F. Martin Carli, Alicja A. Skowronski, Qi Sun, Joel Eriksson, Liesbeth Vandenput, Dan Mellström, Mattias Lorentzon, Claes Ohlsson, John-Olov Jansson
Nature Communications - 2016
Six Tissue Transcriptomics Reveals Specific Immune Suppression in Spleen by Dietary Polyunsaturated Fatty
Acids

Sara L Svahn, Leif Väremo, Britt G. Gabrielsson, Eduard Peris, Intawat Nookaew, Louise Grahnemo, Ann-Sofie Sandberg, Ingrid Wernstedt Asterholm, John-Olov Jansson, Jens B. Nielsen, Maria E Johansson
PLoS ONE - 2016
Regulation of body fat mass by the gut microbiota: Possible mediation by the
brain.

Erik Schéle, Louise Grahnemo, Fredrik Anesten, Anna Hallén, Fredrik Bäckhed, John-Olov Jansson
Peptides - 2016
Dietary polyunsaturated fatty acids increase survival and decrease bacterial load during septic S. aureus infection, and improve neutrophil function in
mice

Sara L Svahn, Louise Grahnemo, Vilborg Palsdottir, Intawat Nookaew, Karl Wendt, Britt G. Gabrielsson, Erik Scheele, Anna Benrick, Niklas Andersson, Staffan Nilsson, Maria E Johansson, John-Olov Jansson
Infection and Immunity - 2015
The androgen receptor confers protection against diet-induced atherosclerosis, obesity, and dyslipidemia in female
mice.

Johan Bourghardt Fagman, Anna S K Wilhelmson, Benedetta Maria Motta, Carlo Pirazzi, Camilla Alexanderson, Karel De Gendt, Guido Verhoeven, Agneta Holmäng, Fredrik Anesten, John-Olov Jansson, Malin Levin, Jan Borén, Claes Ohlsson, Alexandra Krettek, Stefano Romeo, Åsa Tivesten
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2015
Brain IL-6--Where Amylin and GLP-1 Antiobesity Signaling
Congregate.

John-Olov Jansson, Vilborg Palsdottir
Diabetes - 2015
Ghrelin.

T D Müller, R Nogueiras, M L Andermann, Z B Andrews, S D Anker, J Argente, R L Batterham, S C Benoit, C Y Bowers, F Broglio, F F Casanueva, D D'Alessio, I Depoortere, A Geliebter, E Ghigo, P A Cole, M Cowley, D E Cummings, A Dagher, S Diano, Suzanne L. Dickson, C Diéguez, R Granata, H J Grill, K Grove, K M Habegger, K Heppner, M L Heiman, L Holsen, B Holst, A Inui, John-Olov Jansson, H Kirchner, M Korbonits, B Laferrère, C W LeRoux, M Lopez, S Morin, M Nakazato, R Nass, D Perez-Tilve, P T Pfluger, T W Schwartz, R J Seeley, M Sleeman, Y Sun, L Sussel, J Tong, M O Thorner, A J van der Lely, L H T van der Ploeg, J M Zigman, M Kojima, K Kangawa, R G Smith, T Horvath, M H Tschöp
Molecular metabolism - 2015
GLP-1 Receptor Stimulation of the Lateral Parabrachial Nucleus Reduces Food Intake: Neuroanatomical, Electrophysiological, and Behavioral
Evidence

Jennifer E. Richard, I. Farkas, Fredrik Anesten, Rozita H Anderberg, Suzanne L. Dickson, F. M. Gribble, F. Reimann, John-Olov Jansson, Z. Liposits, Karolina P Skibicka
Endocrinology - 2014
The gut microbiota reduces leptin sensitivity and the expression of the obesity-suppressing neuropeptides proglucagon (Gcg) and brain-derived neurotrophic factor (Bdnf) in the central nervous
system.

Erik Schéle, Louise Grahnemo, Fredrik Anesten, Anna Hallén, Fredrik Bäckhed, John-Olov Jansson
Endocrinology - 2013
Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and
IL-6

Rozita H. Shirazi, Vilborg Palsdottir, Jim Collander, Fredrik Anesten, Heike Vogel, F. Langlet, A. Jaschke, A. Schurmann, V. Prevot, Linus Ruijin Shao, John-Olov Jansson, Karolina P Skibicka
Proceedings of the National Academy of Sciences of the United States of America - 2013
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic
architecture

SI Berndt, Liesbeth Vandenput, John-Olov Jansson, Mattias Lorentzon, Claes Ohlsson
Nature Genetics - 2013
Interrelation between interleukin-1 (IL-1), IL-6 and body fat regulating circuits of the hypothalamic arcuate
nucleus.

Erik Schéle, Anna Benrick, Louise Grahnemo, Emil Egecioglu, Fredrik Anesten, Vilborg Palsdottir, John-Olov Jansson
Journal of neuroendocrinology - 2013
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82
studies

N Sarwar, Svetlana Adamovic, Dan Mellström, John-Olov Jansson, Claes Ohlsson, Åsa Tivesten
The Lancet - 2012
Interleukin-6 Receptor alpha is Co-localised with Melanin-Concentrating Hormone in Human and Mouse
Hypothalamus

Erik Schéle, C. Fekete, P. Egri, T. Fuzesi, M. Palkovits, E. Keller, Z. Liposits, B. Gereben, Linda Karlsson-Lindahl, Linus Ruijin Shao, John-Olov Jansson
Journal of Neuroendocrinology - 2012
Heparanase affects food intake and regulates energy balance in
mice.

Linda Karlsson-Lindahl, Linnéa Schmidt, David Haage, Caroline Hansson, Magdalena Taube, Emil Egecioglu, Ying-xia Tan, Therese Admyre, John-Olov Jansson, Israel Vlodavsky, Jin-Ping Li, Ulf Lindahl, Suzanne L. Dickson
PloS one - 2012
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone
regulation.

Andrea D Coviello, Robin Haring, Melissa Wellons, Dhananjay Vaidya, Terho Lehtimäki, Sarah Keildson, Kathryn L Lunetta, Chunyan He, Myriam Fornage, Vasiliki Lagou, Massimo Mangino, N Charlotte Onland-Moret, Brian Chen, Joel Eriksson, Melissa Garcia, Yong Mei Liu, Annemarie Koster, Kurt Lohman, Leo-Pekka Lyytikäinen, Ann-Kristin Petersen, Jennifer Prescott, Lisette Stolk, Liesbeth Vandenput, Andrew R Wood, Wei Vivian Zhuang, Aimo Ruokonen, Anna-Liisa Hartikainen, Anneli Pouta, Stefania Bandinelli, Reiner Biffar, Georg Brabant, David G Cox, Yuhui Chen, Steven Cummings, Luigi Ferrucci, Marc J Gunter, Susan E Hankinson, Hannu Martikainen, Albert Hofman, Georg Homuth, Thomas Illig, John-Olov Jansson, Andrew D Johnson, David Karasik, Magnus Karlsson, Johannes Kettunen, Douglas P Kiel, Peter Kraft, Jingmin Liu, Osten Ljunggren, Mattias Lorentzon, Marcello Maggio, Marcello R P Markus, Dan Mellström, Iva Miljkovic, Daniel Mirel, Sarah Nelson, Laure Morin Papunen, Petra H M Peeters, Inga Prokopenko, Leslie Raffel, Martin Reincke, Alex P Reiner, Kathryn Rexrode, Fernando Rivadeneira, Stephen M Schwartz, David Siscovick, Nicole Soranzo, Doris Stöckl, Shelley Tworoger, André G Uitterlinden, Carla H van Gils, Ramachandran S Vasan, H-Erich Wichmann, Guangju Zhai, Shalender Bhasin, Martin Bidlingmaier, Stephen J Chanock, Immaculata De Vivo, Tamara B Harris, David J Hunter, Mika Kähönen, Simin Liu, Pamela Ouyang, Tim D Spector, Yvonne T van der Schouw, Jorma Viikari, Henri Wallaschofski, Mark I McCarthy, Timothy M Frayling, Anna Murray, Steve Franks, Marjo-Riitta Järvelin, Frank H de Jong, Olli Raitakari, Alexander Teumer, Claes Ohlsson, Joanne M Murabito, John R B Perry
PLoS genetics - 2012
Association study of POMC variants with body composition measures and nutrient
choice.

Andrew Ternouth, Marek K Brandys, Yvonne T van der Schouw, Judith Hendriks, John-Olov Jansson, David Collier, Roger A. H. Adan
European journal of pharmacology - 2011
Liver-derived igf-I regulates mean life span in
mice

Johan Svensson, Klara Sjögren, Jenny Fäldt, Niklas Andersson, Olle Isaksson, John-Olov Jansson, Claes Ohlsson
PLoS ONE - 2011
Perinatal lack of maternal IL-6 promotes increased adiposity during adulthood in
mice.

Susanne Lager, Ingrid Wernstedt Asterholm, Erik Schéle, Nina Jansson, Staffan Nilsson, John-Olov Jansson, Malin Lönn, Agneta Holmäng
Endocrinology - 2011
Genetic Association and Gene Expression Analysis Identify FGFR1 as a New Susceptibility Gene for Human
Obesity.

Hong Jiao, Peter Arner, Suzanne L. Dickson, Hubert Vidal, Niklas Mejhert, Corneliu Henegar, Magdalena Taube, Caroline Hansson, Anke Hinney, Pilar Galan, Chantal Simon, Angela Silveira, Anna Benrick, John-Olov Jansson, Anne Bouloumié, Dominique Langin, Martine Laville, Cyrille Debard, Tomas Axelsson, Mikael Rydén, Juha Kere, Karin Dahlman-Wright, Anders Hamsten, Karine Clement, Ingrid Dahlman
The Journal of clinical endocrinology and metabolism - 2011
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268
children.

Tuomas O Kilpeläinen, Lu Qi, Soren Brage, Stephen J Sharp, Emily Sonestedt, Ellen Demerath, Tariq Ahmad, Samia Mora, Marika Kaakinen, Camilla Helene Sandholt, Christina Holzapfel, Christine S Autenrieth, Elina Hyppönen, Stéphane Cauchi, Meian He, Zoltan Kutalik, Meena Kumari, Alena Stančáková, Karina Meidtner, Beverley Balkau, Jonathan T Tan, Massimo Mangino, Nicholas J Timpson, Yiqing Song, M Carola Zillikens, Kathleen A Jablonski, Melissa E Garcia, Stefan Johansson, Jennifer L Bragg-Gresham, Ying Wu, Jana V van Vliet-Ostaptchouk, N Charlotte Onland-Moret, Esther Zimmermann, Natalia V Rivera, Toshiko Tanaka, Heather M Stringham, Günther Silbernagel, Stavroula Kanoni, Mary F Feitosa, Soren Snitker, Jonatan R Ruiz, Jeffery Metter, Maria Teresa Martinez Larrad, Mustafa Atalay, Maarit Hakanen, Najaf Amin, Christine Cavalcanti-Proença, Anders Grøntved, Göran Hallmans, John-Olov Jansson, Johanna Kuusisto, Mika Kähönen, Pamela L Lutsey, John J Nolan, Luigi Palla, Oluf Pedersen, Louis Pérusse, Frida Renström, Robert A Scott, Dmitry Shungin, Ulla Sovio, Tuija H Tammelin, Tapani Rönnemaa, Timo A Lakka, Matti Uusitupa, Manuel Serrano Rios, Luigi Ferrucci, Claude Bouchard, Aline Meirhaeghe, Mao Fu, Mark Walker, Ingrid B Borecki, George V Dedoussis, Andreas Fritsche, Claes Ohlsson, Michael Boehnke, Stefania Bandinelli, Cornelia M van Duijn, Shah Ebrahim, Debbie A Lawlor, Vilmundur Gudnason, Tamara B Harris, Thorkild I A Sørensen, Karen L Mohlke, Albert Hofman, André G Uitterlinden, Jaakko Tuomilehto, Terho Lehtimäki, Olli Raitakari, Bo Isomaa, Pål R Njølstad, Jose C Florez, Simin Liu, Andy Ness, Timothy D Spector, E Shyong Tai, Philippe Froguel, Heiner Boeing, Markku Laakso, Michael Marmot, Sven Bergmann, Chris Power, Kay-Tee Khaw, Daniel Chasman, Paul Ridker, Torben Hansen, Keri L Monda, Thomas Illig, Marjo-Riitta Järvelin, Nicholas J Wareham, Frank B Hu, Leif C Groop, Marju Orho-Melander, Ulf Ekelund, Paul W Franks, Ruth J F Loos
PLoS medicine - 2011
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic
profile.

Tuomas O Kilpeläinen, M Carola Zillikens, Alena Stančákova, Francis M Finucane, Janina S Ried, Claudia Langenberg, Weihua Zhang, Jacques S Beckmann, Jian'an Luan, Liesbeth Vandenput, Unnur Styrkarsdottir, Yanhua Zhou, Albert Vernon Smith, Jing-Hua Zhao, Najaf Amin, Sailaja Vedantam, So-Youn Shin, Talin Haritunians, Mao Fu, Mary F Feitosa, Meena Kumari, Bjarni V Halldorsson, Emmi Tikkanen, Massimo Mangino, Caroline Hayward, Ci Song, Alice M Arnold, Yurii S Aulchenko, Ben A Oostra, Harry Campbell, L Adrienne Cupples, Kathryn E Davis, Angela Döring, Gudny Eiriksdottir, Karol Estrada, José Manuel Fernández-Real, Melissa Garcia, Christian Gieger, Nicole L Glazer, Candace Guiducci, Albert Hofman, Steve E Humphries, Bo Isomaa, Leonie C Jacobs, Antti Jula, David Karasik, Magnus K Karlsson, Kay-Tee Khaw, Lauren J Kim, Mika Kivimäki, Norman Klopp, Brigitte Kühnel, Johanna Kuusisto, Yongmei Liu, Osten Ljunggren, Mattias Lorentzon, Robert N Luben, Barbara McKnight, Dan Mellström, Braxton D Mitchell, Vincent Mooser, José Maria Moreno, Satu Männistö, Jeffery R O'Connell, Laura Pascoe, Leena Peltonen, Belén Peral, Markus Perola, Bruce M Psaty, Veikko Salomaa, David B Savage, Robert K Semple, Tatjana Skaric-Juric, Gunnar Sigurdsson, Kijoung S Song, Timothy D Spector, Ann-Christine Syvänen, Philippa J Talmud, Gudmar Thorleifsson, Unnur Thorsteinsdottir, André G Uitterlinden, Cornelia M van Duijn, Antonio Vidal-Puig, Sarah H Wild, Alan F Wright, Deborah J Clegg, Eric Schadt, James F Wilson, Igor Rudan, Samuli Ripatti, Ingrid B Borecki, Alan R Shuldiner, Erik Ingelsson, John-Olov Jansson, Robert C Kaplan, Vilmundur Gudnason, Tamara B Harris, Leif Groop, Douglas P Kiel, Fernando Rivadeneira, Mark Walker, Inês Barroso, Peter Vollenweider, Gérard Waeber, John C Chambers, Jaspal S Kooner, Nicole Soranzo, Joel N Hirschhorn, Kari Stefansson, H-Erich Wichmann, Claes Ohlsson, Stephen O'Rahilly, Nicholas J Wareham, Elizabeth K Speliotes, Caroline S Fox, Markku Laakso, Ruth J F Loos
Nature genetics - 2011
Genetic determinants of serum testosterone concentrations in
men.

Claes Ohlsson, Henri Wallaschofski, Kathryn L Lunetta, Lisette Stolk, John R B Perry, Annemarie Koster, Ann-Kristin Petersen, Joel Eriksson, Terho Lehtimäki, Ilpo T Huhtaniemi, Geoffrey L Hammond, Marcello Maggio, Andrea D Coviello, Luigi Ferrucci, Margit Heier, Albert Hofman, Kate L Holliday, John-Olov Jansson, Mika Kähönen, David Karasik, Magnus K Karlsson, Douglas P Kiel, Yongmei Liu, Osten Ljunggren, Mattias Lorentzon, Leo-Pekka Lyytikäinen, Thomas Meitinger, Dan Mellström, David Melzer, Iva Miljkovic, Matthias Nauck, Maria Nilsson, Brenda Penninx, Stephen R Pye, Ramachandran S Vasan, Martin Reincke, Fernando Rivadeneira, Abdelouahid Tajar, Alexander Teumer, André G Uitterlinden, Jagadish Ulloor, Jorma Viikari, Uwe Völker, Henry Völzke, H Erich Wichmann, Tsung-Sheng Wu, Wei Vivian Zhuang, Elad Ziv, Frederick C W Wu, Olli Raitakari, Anna-Lena Eriksson, Martin Bidlingmaier, Tamara B Harris, Anna Murray, Frank H de Jong, Joanne M Murabito, Shalender Bhasin, Liesbeth Vandenput, Robin Haring
PLoS genetics - 2011
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic
traits.

Elizabeth K Speliotes, Laura M Yerges-Armstrong, Jun Wu, Ruben Hernaez, Lauren J Kim, Cameron D Palmer, Vilmundur Gudnason, Gudny Eiriksdottir, Melissa E Garcia, Lenore J Launer, Michael A Nalls, Jeanne M Clark, Braxton D Mitchell, Alan R Shuldiner, Johannah L Butler, Marta Tomas, Udo Hoffmann, Shih-Jen Hwang, Joseph M Massaro, Christopher J O'Donnell, Dushyant V Sahani, Veikko Salomaa, Eric E Schadt, Stephen M Schwartz, David S Siscovick, (NASH CRN) NASH Clinical Research Network, Consortium Giant, Investigators MAGIC, Benjamin F Voight, J Jeffrey Carr, Mary F Feitosa, Tamara B Harris, Caroline S Fox, Albert V Smith, W H Linda Kao, Joel N Hirschhorn, Ingrid B Borecki, Consortium GOLD, John-Olov Jansson
PLoS genetics - 2011
A variant near the interleukin-6 gene is associated with fat mass in Caucasian
men

Niklas Andersson, Louise Strandberg, Staffan Nilsson, Svetlana Adamovic, M. K. Karlsson, O. Ljunggren, Dan Mellström, N. E. Lane, J. M. Zmuda, C. Nielsen, E. Orwoll, Mattias Lorentzon, Claes Ohlsson, John-Olov Jansson
International Journal of Obesity - 2010
Ghrelinbrist efter gastrektomi möjlig indikation för
ghrelinanaloger.

Johan Svensson, John-Olov Jansson
Läkartidningen - 2010
Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin
resistance.

V B Matthews, T L Allen, S Risis, M H S Chan, D C Henstridge, N Watson, L A Zaffino, J R Babb, J Boon, P J Meikle, J B Jowett, M J Watt, John-Olov Jansson, C R Bruce, M A Febbraio
Diabetologia - 2010
Edentulism associated with obesity: a study of four national surveys of 16 416 Swedes aged 55-84
years.

Tor Österberg, Debashish Kumar Dey, Valter Sundh, Gunnar E Carlsson, John-Olov Jansson, Dan Mellström
Acta odontologica Scandinavica - 2010
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass
index.

Elizabeth K Speliotes, Cristen J Willer, Sonja I Berndt, Keri L Monda, Gudmar Thorleifsson, Anne U Jackson, Hana Lango Allen, Cecilia M Lindgren, Jian'an Luan, Reedik Mägi, Joshua C Randall, Sailaja Vedantam, Thomas W Winkler, Lu Qi, Tsegaselassie Workalemahu, Iris M Heid, Valgerdur Steinthorsdottir, Heather M Stringham, Michael N Weedon, Eleanor Wheeler, Andrew R Wood, Teresa Ferreira, Robert J Weyant, Ayellet V Segrè, Karol Estrada, Liming Liang, James Nemesh, Ju-Hyun Park, Stefan Gustafsson, Tuomas O Kilpeläinen, Jian Yang, Nabila Bouatia-Naji, Tõnu Esko, Mary F Feitosa, Zoltán Kutalik, Massimo Mangino, Soumya Raychaudhuri, Andre Scherag, Albert Vernon Smith, Ryan Welch, Jing Hua Zhao, Katja K Aben, Devin M Absher, Najaf Amin, Anna L Dixon, Eva Fisher, Nicole L Glazer, Michael E Goddard, Nancy L Heard-Costa, Volker Hoesel, Jouke-Jan Hottenga, Åsa Johansson, Toby Johnson, Shamika Ketkar, Claudia Lamina, Shengxu Li, Miriam F Moffatt, Richard H Myers, Narisu Narisu, John R B Perry, Marjolein J Peters, Michael Preuss, Samuli Ripatti, Fernando Rivadeneira, Camilla Sandholt, Laura J Scott, Nicholas J Timpson, Jonathan P Tyrer, Sophie van Wingerden, Richard M Watanabe, Charles C White, Fredrik Wiklund, Christina Barlassina, Daniel I Chasman, Matthew N Cooper, John-Olov Jansson, Robert W Lawrence, Niina Pellikka, Inga Prokopenko, Jianxin Shi, Elisabeth Thiering, Helene Alavere, Maria T S Alibrandi, Peter Almgren, Alice M Arnold, Thor Aspelund, Larry D Atwood, Beverley Balkau, Anthony J Balmforth, Amanda J Bennett, Yoav Ben-Shlomo, Richard N Bergman, Sven Bergmann, Heike Biebermann, Alexandra I F Blakemore, Tanja Boes, Lori L Bonnycastle, Stefan R Bornstein, Morris J Brown, Thomas A Buchanan, Fabio Busonero, Harry Campbell, Francesco P Cappuccio, Christine Cavalcanti-Proença, Yii-Der Ida Chen, Chih-Mei Chen, Peter S Chines, Robert Clarke, Lachlan Coin, John Connell, Ian N M Day, Martin den Heijer, Jubao Duan, Shah Ebrahim, Paul Elliott, Roberto Elosua, Gudny Eiriksdottir, Michael R Erdos, Johan G Eriksson, Maurizio F Facheris, Stephan B Felix, Pamela Fischer-Posovszky, Aaron R Folsom, Nele Friedrich, Nelson B Freimer, Mao Fu, Stefan Gaget, Pablo V Gejman, Eco J C Geus, Christian Gieger, Anette P Gjesing, Anuj Goel, Philippe Goyette, Harald Grallert, Jürgen Gräßler, Danielle M Greenawalt, Christopher J Groves, Vilmundur Gudnason, Candace Guiducci, Anna-Liisa Hartikainen, Neelam Hassanali, Alistair S Hall, Aki S Havulinna, Caroline Hayward, Andrew C Heath, Christian Hengstenberg, Andrew A Hicks, Anke Hinney, Albert Hofman, Georg Homuth, Jennie Hui, Wilmar Igl, Carlos Iribarren, Bo Isomaa, Kevin B Jacobs, Ivonne Jarick, Elizabeth Jewell, Ulrich John, Torben Jørgensen, Pekka Jousilahti, Antti Jula, Marika Kaakinen, Eero Kajantie, Lee M Kaplan, Sekar Kathiresan, Johannes Kettunen, Leena Kinnunen, Joshua W Knowles, Ivana Kolcic, Inke R König, Seppo Koskinen, Peter Kovacs, Johanna Kuusisto, Peter Kraft, Kirsti Kvaløy, Jaana Laitinen, Olivier Lantieri, Chiara Lanzani, Lenore J Launer, Cecile Lecoeur, Terho Lehtimäki, Guillaume Lettre, Jianjun Liu, Marja-Liisa Lokki, Mattias Lorentzon, Robert N Luben, Barbara Ludwig, Paolo Manunta, Diana Marek, Michel Marre, Nicholas G Martin, Wendy L McArdle, Anne McCarthy, Barbara McKnight, Thomas Meitinger, Olle Melander, David Meyre, Kristian Midthjell, Grant W Montgomery, Mario A Morken, Andrew P Morris, Rosanda Mulic, Julius S Ngwa, Mari Nelis, Matt J Neville, Dale R Nyholt, Christopher J O'Donnell, Stephen O'Rahilly, Ken K Ong, Ben Oostra, Guillaume Paré, Alex N Parker, Markus Perola, Irene Pichler, Kirsi H Pietiläinen, Carl G P Platou, Ozren Polasek, Anneli Pouta, Suzanne Rafelt, Olli Raitakari, Nigel W Rayner, Martin Ridderstråle, Winfried Rief, Aimo Ruokonen, Neil R Robertson, Peter Rzehak, Veikko Salomaa, Alan R Sanders, Manjinder S Sandhu, Serena Sanna, Jouko Saramies, Markku J Savolainen, Susann Scherag, Sabine Schipf, Stefan Schreiber, Heribert Schunkert, Kaisa Silander, Juha Sinisalo, David S Siscovick, Jan H Smit, Nicole Soranzo, Ulla Sovio, Jonathan Stephens, Ida Surakka, Amy J Swift, Mari-Liis Tammesoo, Jean-Claude Tardif, Maris Teder-Laving, Tanya M Teslovich, John R Thompson, Brian Thomson, Anke Tönjes, Tiinamaija Tuomi, Joyce B J van Meurs, Gert-Jan van Ommen, Vincent Vatin, Jorma Viikari, Sophie Visvikis-Siest, Veronique Vitart, Carla I G Vogel, Benjamin F Voight, Lindsay L Waite, Henri Wallaschofski, G Bragi Walters, Elisabeth Widen, Susanna Wiegand, Sarah H Wild, Gonneke Willemsen, Daniel R Witte, Jacqueline C Witteman, Jianfeng Xu, Qunyuan Zhang, Lina Zgaga, Andreas Ziegler, Paavo Zitting, John P Beilby, I Sadaf Farooqi, Johannes Hebebrand, Heikki V Huikuri, Alan L James, Mika Kähönen, Douglas F Levinson, Fabio Macciardi, Markku S Nieminen, Claes Ohlsson, Lyle J Palmer, Paul M Ridker, Michael Stumvoll, Jacques S Beckmann, Heiner Boeing, Eric Boerwinkle, Dorret I Boomsma, Mark J Caulfield, Stephen J Chanock, Francis S Collins, L Adrienne Cupples, George Davey Smith, Jeanette Erdmann, Philippe Froguel, Henrik Grönberg, Ulf Gyllensten, Per Hall, Torben Hansen, Tamara B Harris, Andrew T Hattersley, Richard B Hayes, Joachim Heinrich, Frank B Hu, Kristian Hveem, Thomas Illig, Marjo-Riitta Jarvelin, Jaakko Kaprio, Fredrik Karpe, Kay-Tee Khaw, Lambertus A Kiemeney, Heiko Krude, Markku Laakso, Debbie A Lawlor, Andres Metspalu, Patricia B Munroe, Willem H Ouwehand, Oluf Pedersen, Brenda W Penninx, Annette Peters, Peter P Pramstaller, Thomas Quertermous, Thomas Reinehr, Aila Rissanen, Igor Rudan, Nilesh J Samani, Peter E H Schwarz, Alan R Shuldiner, Timothy D Spector, Jaakko Tuomilehto, Manuela Uda, André Uitterlinden, Timo T Valle, Martin Wabitsch, Gérard Waeber, Nicholas J Wareham, Hugh Watkins, James F Wilson, Alan F Wright, M Carola Zillikens, Nilanjan Chatterjee, Steven A McCarroll, Shaun Purcell, Eric E Schadt, Peter M Visscher, Themistocles L Assimes, Ingrid B Borecki, Panos Deloukas, Caroline S Fox, Leif C Groop, Talin Haritunians, David J Hunter, Robert C Kaplan, Karen L Mohlke, Jeffrey R O'Connell, Leena Peltonen, David Schlessinger, David P Strachan, Cornelia M van Duijn, H-Erich Wichmann, Timothy M Frayling, Unnur Thorsteinsdottir, Gonçalo R Abecasis, Inês Barroso, Michael Boehnke, Kari Stefansson, Kari E North, Mark I McCarthy, Joel N Hirschhorn, Erik Ingelsson, Ruth J F Loos
Nature genetics - 2010
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat
distribution.

Iris M Heid, Anne U Jackson, Joshua C Randall, Thomas W Winkler, Lu Qi, Valgerdur Steinthorsdottir, Gudmar Thorleifsson, M Carola Zillikens, Elizabeth K Speliotes, Reedik Mägi, Tsegaselassie Workalemahu, Charles C White, Nabila Bouatia-Naji, Tamara B Harris, Sonja I Berndt, Erik Ingelsson, Cristen J Willer, Michael N Weedon, Jian'an Luan, Sailaja Vedantam, Tõnu Esko, Tuomas O Kilpeläinen, Zoltán Kutalik, Shengxu Li, Keri L Monda, Anna L Dixon, Christopher C Holmes, Lee M Kaplan, Liming Liang, Josine L Min, Miriam F Moffatt, Cliona Molony, George Nicholson, Eric E Schadt, Krina T Zondervan, Mary F Feitosa, Teresa Ferreira, Hana Lango Allen, Robert J Weyant, Eleanor Wheeler, Andrew R Wood, Karol Estrada, Michael E Goddard, Guillaume Lettre, Massimo Mangino, Dale R Nyholt, Shaun Purcell, Albert Vernon Smith, Peter M Visscher, Jian Yang, Steven A McCarroll, James Nemesh, Benjamin F Voight, Devin Absher, Najaf Amin, Thor Aspelund, Lachlan Coin, Nicole L Glazer, Caroline Hayward, Nancy L Heard-Costa, Jouke-Jan Hottenga, Åsa Johansson, Toby Johnson, Marika Kaakinen, Karen Kapur, Shamika Ketkar, Joshua W Knowles, Peter Kraft, Aldi T Kraja, Claudia Lamina, Michael F Leitzmann, Barbara McKnight, Andrew P Morris, Ken K Ong, John R B Perry, Marjolein J Peters, Ozren Polasek, Inga Prokopenko, Nigel W Rayner, Samuli Ripatti, Fernando Rivadeneira, Neil R Robertson, Serena Sanna, Ulla Sovio, Ida Surakka, Alexander Teumer, Sophie van Wingerden, Veronique Vitart, Jing Hua Zhao, Christine Cavalcanti-Proença, Peter S Chines, Eva Fisher, Jennifer R Kulzer, Cecile Lecoeur, Narisu Narisu, Camilla Sandholt, Laura J Scott, Kaisa Silander, Klaus Stark, Mari-Liis Tammesoo, Tanya M Teslovich, Nicholas John Timpson, Richard M Watanabe, Ryan Welch, Daniel I Chasman, Matthew N Cooper, John-Olov Jansson, Johannes Kettunen, Robert W Lawrence, Niina Pellikka, Markus Perola, Liesbeth Vandenput, Helene Alavere, Peter Almgren, Larry D Atwood, Amanda J Bennett, Reiner Biffar, Lori L Bonnycastle, Stefan R Bornstein, Thomas A Buchanan, Harry Campbell, Ian N M Day, Mariano Dei, Marcus Dörr, Paul Elliott, Michael R Erdos, Johan G Eriksson, Nelson B Freimer, Mao Fu, Stefan Gaget, Eco J C Geus, Anette P Gjesing, Harald Grallert, Jürgen Gräßler, Christopher J Groves, Candace Guiducci, Anna-Liisa Hartikainen, Neelam Hassanali, Aki S Havulinna, Karl-Heinz Herzig, Andrew A Hicks, Jennie Hui, Wilmar Igl, Pekka Jousilahti, Antti Jula, Eero Kajantie, Leena Kinnunen, Ivana Kolcic, Seppo Koskinen, Peter Kovacs, Heyo K Kroemer, Vjekoslav Krzelj, Johanna Kuusisto, Kirsti Kvaloy, Jaana Laitinen, Olivier Lantieri, G Mark Lathrop, Marja-Liisa Lokki, Robert N Luben, Barbara Ludwig, Wendy L McArdle, Anne McCarthy, Mario A Morken, Mari Nelis, Matt J Neville, Guillaume Paré, Alex N Parker, John F Peden, Irene Pichler, Kirsi H Pietiläinen, Carl G P Platou, Anneli Pouta, Martin Ridderstråle, Nilesh J Samani, Jouko Saramies, Juha Sinisalo, Jan H Smit, Rona J Strawbridge, Heather M Stringham, Amy J Swift, Maris Teder-Laving, Brian Thomson, Gianluca Usala, Joyce B J van Meurs, Gert-Jan van Ommen, Vincent Vatin, Claudia B Volpato, Henri Wallaschofski, G Bragi Walters, Elisabeth Widen, Sarah H Wild, Gonneke Willemsen, Daniel R Witte, Lina Zgaga, Paavo Zitting, John P Beilby, Alan L James, Mika Kähönen, Terho Lehtimäki, Markku S Nieminen, Claes Ohlsson, Lyle J Palmer, Olli Raitakari, Paul M Ridker, Michael Stumvoll, Anke Tönjes, Jorma Viikari, Beverley Balkau, Yoav Ben-Shlomo, Richard N Bergman, Heiner Boeing, George Davey Smith, Shah Ebrahim, Philippe Froguel, Torben Hansen, Christian Hengstenberg, Kristian Hveem, Bo Isomaa, Torben Jørgensen, Fredrik Karpe, Kay-Tee Khaw, Markku Laakso, Debbie A Lawlor, Michel Marre, Thomas Meitinger, Andres Metspalu, Kristian Midthjell, Oluf Pedersen, Veikko Salomaa, Peter E H Schwarz, Tiinamaija Tuomi, Jaakko Tuomilehto, Timo T Valle, Nicholas J Wareham, Alice M Arnold, Jacques S Beckmann, Sven Bergmann, Eric Boerwinkle, Dorret I Boomsma, Mark J Caulfield, Francis S Collins, Gudny Eiriksdottir, Vilmundur Gudnason, Ulf Gyllensten, Anders Hamsten, Andrew T Hattersley, Albert Hofman, Frank B Hu, Thomas Illig, Carlos Iribarren, Marjo-Riitta Jarvelin, W H Linda Kao, Jaakko Kaprio, Lenore J Launer, Patricia B Munroe, Ben Oostra, Brenda W Penninx, Peter P Pramstaller, Bruce M Psaty, Thomas Quertermous, Aila Rissanen, Igor Rudan, Alan R Shuldiner, Nicole Soranzo, Timothy D Spector, Ann-Christine Syvanen, Manuela Uda, André Uitterlinden, Henry Völzke, Peter Vollenweider, James F Wilson, Jacqueline C Witteman, Alan F Wright, Gonçalo R Abecasis, Michael Boehnke, Ingrid B Borecki, Panos Deloukas, Timothy M Frayling, Leif C Groop, Talin Haritunians, David J Hunter, Robert C Kaplan, Kari E North, Jeffrey R O'Connell, Leena Peltonen, David Schlessinger, David P Strachan, Joel N Hirschhorn, Themistocles L Assimes, H-Erich Wichmann, Unnur Thorsteinsdottir, Cornelia M van Duijn, Kari Stefansson, L Adrienne Cupples, Ruth J F Loos, Inês Barroso, Mark I McCarthy, Caroline S Fox, Karen L Mohlke, Cecilia M Lindgren
Nature genetics - 2010
Common genetic determinants of vitamin D insufficiency: a genome-wide association
study.

Thomas J Wang, Feng Zhang, J Brent Richards, Bryan Kestenbaum, Joyce B van Meurs, Diane Berry, Douglas P Kiel, Elizabeth A Streeten, Claes Ohlsson, Daniel L Koller, Leena Peltonen, Jason D Cooper, Paul F O'Reilly, Denise K Houston, Nicole L Glazer, Liesbeth Vandenput, Munro Peacock, Julia Shi, Fernando Rivadeneira, Mark I McCarthy, Pouta Anneli, Ian H de Boer, Massimo Mangino, Bernet Kato, Deborah J Smyth, Sarah L Booth, Paul F Jacques, Greg L Burke, Mark Goodarzi, Ching-Lung Cheung, Myles Wolf, Kenneth Rice, David Goltzman, Nick Hidiroglou, Martin Ladouceur, Nicholas J Wareham, Lynne J Hocking, Deborah Hart, Nigel K Arden, Cyrus Cooper, Suneil Malik, William D Fraser, Anna-Liisa Hartikainen, Guangju Zhai, Helen M Macdonald, Nita G Forouhi, Ruth Jf Loos, David M Reid, Alan Hakim, Elaine Dennison, Yongmei Liu, Chris Power, Helen E Stevens, Laitinen Jaana, Ramachandran S Vasan, Nicole Soranzo, Jörg Bojunga, Bruce M Psaty, Mattias Lorentzon, Tatiana Foroud, Tamara B Harris, Albert Hofman, John-Olov Jansson, Jane A Cauley, Andre G Uitterlinden, Quince Gibson, Marjo-Riitta Järvelin, David Karasik, David S Siscovick, Michael J Econs, Stephen B Kritchevsky, Jose C Florez, John A Todd, Josee Dupuis, Elina Hyppönen, Timothy D Spector
Lancet - 2010
Variants of the interleukin-1 receptor antagonist gene are associated with fat mass in
men.

Niklas Andersson, Louise Strandberg, Staffan Nilsson, Ö Ljungren, Magnus K Karlsson, Dan Mellström, Mattias Lorentzon, Claes Ohlsson, John-Olov Jansson
International journal of obesity (2005) - 2009
Mice chronically fed high-fat diet have increased mortality and disturbed immune response in
sepsis.

Louise Strandberg, Margareta Verdrengh, Maria Enge, Niklas Andersson, Sylvie Amu, Karin Önnheim, Anna Benrick, Mikael Brisslert, Johan Bylund, Maria Bokarewa, Staffan Nilsson, John-Olov Jansson
PloS one - 2009
Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis
elegans

Catarina Mörck, L. Olsen, C. Kurth, Annelie Persson, N. J. Storm, Emma Svensson, John-Olov Jansson, Marika Hellqvist, Annika Enejder, N. J. Faergeman, Marc Pilon
Proceedings of the National Academy of Sciences - 2009
A missense mutation in the non-neural G-protein alpha-subunit isoforms modulates susceptibility to
obesity.

M L Kelly, L Moir, L Jones, E Whitehill, Q M Anstee, R D Goldin, A Hough, M Cheeseman, John-Olov Jansson, J. Petersen, R D Cox
International journal of obesity - 2009
The role of liver-derived insulin-like growth
factor-I.

Claes Ohlsson, Subburaman Mohan, Klara Sjögren, Åsa Tivesten, Jörgen Isgaard, Olle Isaksson, John-Olov Jansson, Johan Svensson
Endocrine reviews - 2009
Interleukin-6 gene knockout influences energy balance regulating peptides in the hypothalamic paraventricular and supraoptic
nuclei.

Anna Benrick, Erik Schéle, S B Pinnock, Ingrid Wernstedt Asterholm, Suzanne L. Dickson, Linda Karlsson-Lindahl, John-Olov Jansson
Journal of neuroendocrinology - 2009
Down-Regulation of Cilia-Localized IL-6R{alpha} by 17{beta}-Estradiol in Mouse and Human Fallopian
Tubes.

Linus Ruijin Shao, Magdalena Nutu, Linda Karlsson-Lindahl, Anna Benrick, Birgitta Weijdegård, Susanne Lager, Emil Egecioglu, Julia Fernandez-Rodriguez, Christina Gemzell-Danielsson, Claes Ohlsson, John-Olov Jansson, Håkan Billig
American journal of physiology. Cell physiology - 2009
Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass
index.

Cornelia Huth, Thomas Illig, Christian Herder, Christian Gieger, Harald Grallert, Caren Vollmert, Wolfgang Rathmann, Yasmin H Hamid, Oluf Pedersen, Torben Hansen, Barbara Thorand, Christa Meisinger, Angela Doring, Norman Klopp, Henning Gohlke, Wolfgang Lieb, Christian Hengstenberg, Valeriya Lyssenko, Leif Groop, Helen Ireland, Jeffrey W Stephens, Ingrid Wernstedt Asterholm, John-Olov Jansson, Heiner Boeing, Matthias Mohlig, Heather M Stringham, Michael Boehnke, Jaakko Tuomilehto, Jose-Manuel Fernandez-Real, Abel Lopez-Bermejo, Luis Gallart, Joan Vendrell, Steve E Humphries, Florian Kronenberg, H-Erich Wichmann, Iris M Heid
Annals of medicine - 2009
IL6 and IL1B polymorphisms are associated with fat mass in older men: the MrOS Study
Sweden.

Louise Strandberg, Dan Mellström, Osten Ljunggren, Elin Grundberg, Magnus K Karlsson, Anna H Holmberg, Eric S Orwoll, Anna-Lena Eriksson, Johan Svedberg, Magnus Bengtsson, Claes Ohlsson, John-Olov Jansson
Obesity (Silver Spring, Md.) - 2008
Liver-derived IGF1 enhances the androgenic response in
prostate.

Johan Svensson, Jon Kindblom, Linus Ruijin Shao, Sofia Movérare-Skrtic, Marie Lagerquist, Niklas Andersson, Klara Sjögren, Katrien Venken, Dirk Vanderschueren, John-Olov Jansson, Olle Isaksson, Claes Ohlsson
The Journal of endocrinology - 2008
A non-conservative polymorphism in the IL-6 signal transducer (IL6ST)/gp130 is associated with myocardial infarction in a hypertensive
population.

Anna Benrick, Pernilla Jirholt, Ingrid Wernstedt, Maria Gustafsson, Juergen Scheller, Anna-Lena Eriksson, Jan Borén, Thomas Hedner, Claes Ohlsson, Torleif Härd, Stefan Rose-John, John-Olov Jansson
Regulatory peptides - 2008
Point-counterpoint: Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose
homeostasis.

John-Olov Jansson, Ville Wallenius
Journal of applied physiology (Bethesda, Md. : 1985) - 2007
Effects of long-term exercise and diet intervention on plasma adipokine
concentrations.

Merethe H Rokling-Andersen, Janne E Reseland, Marit B Veieröd, Sigmund A Anderssen, David R Jacobs, Petter Urdal, John-Olov Jansson, Christian A Drevon
The American journal of clinical nutrition - 2007
Interleukin-1 system gene polymorphisms are associated with fat mass in young
men.

Louise Strandberg, Mattias Lorentzon, Åsa Hellqvist, Staffan Nilsson, Ville Wallenius, Claes Ohlsson, John-Olov Jansson
The Journal of clinical endocrinology and metabolism - 2006
Reduced stress- and cold-induced increase in energy expenditure in interleukin-6-deficient
mice.

Ingrid Wernstedt, Amanda Edgley, Anna Berndtsson, Jenny Fäldt, Göran Bergström, Ville Wallenius, John-Olov Jansson
American journal of physiology. Regulatory, integrative and comparative physiology - 2006
Mature-onset obesity in interleukin-1 receptor I knockout
mice.

Maria C García, Ingrid Wernstedt, Anna Berndtsson, Maria Enge, Michal Bell, Olof H. Hultgren, Michael Horn, Bo Ahrén, Sven Enerbäck, Claes Ohlsson, Ville Wallenius, John-Olov Jansson
Diabetes - 2006
Endocrine, liver-derived IGF-I is of importance for spatial learning and memory in old
mice.

Johan Svensson, M Diez, Jörgen Engel, Caroline Wass, Åsa Tivesten, John-Olov Jansson, Olle Isaksson, Trevor Archer, Tomas Hökfelt, Claes Ohlsson
The Journal of endocrinology - 2006
Leukemia inhibitory factor reduces body fat mass in ovariectomized
mice

John-Olov Jansson, Sofia Movérare-Skrtic, Anna Berndtsson, Ingrid Wernstedt, Hans Carlsten, Claes Ohlsson
Eur J Endocrinol - 2006
Ghrelin treatment reverses the reduction in weight gain and body fat in gastrectomised
mice.

C Dornonville de la Cour, A. Lindqvist, Emil Egecioglu, Y C L Tung, V Surve, Claes Ohlsson, John-Olov Jansson, C Erlanson-Albertsson, Suzanne L. Dickson, Rolf Håkanson
Gut - 2005
Growth hormone (GH) replacement in women in relation to their endogenous GH
secretion.

John-Olov Jansson, Johan Svensson
The Journal of clinical endocrinology and metabolism - 2004
A common polymorphism in the interleukin-6 gene promoter is associated with
overweight

Ingrid Wernstedt, Anna-Lena Eriksson, Anna Berndtsson, J Hoffstedt, Stanko Skrtic, Thomas Hedner, Lillemor Mattsson Hultén, Olov Wiklund, Claes Ohlsson, John-Olov Jansson
Int J Obes Relat Metab Disord - 2004
Reduced exercise endurance in interleukin-6-deficient
mice

Jenny Fäldt, Ingrid Wernstedt, Sharyn M. Fitzgerald, Kristina Wallenius, Göran Bergström, John-Olov Jansson
Endocrinology - 2004
Interleukin-6 levels in the central nervous system are negatively correlated with fat mass in overweight/obese
subjects.

Kaj Stenlöf, Ingrid Wernstedt, Ted Fjällman, Ville Wallenius, Kristina Wallenius, John-Olov Jansson
The Journal of clinical endocrinology and metabolism - 2003
On the site and mechanism of action of the anti-obesity effects of
interleukin-6.

John-Olov Jansson, Kristina Wallenius, Ingrid Wernstedt, Claes Ohlsson, Suzanne L. Dickson, Ville Wallenius
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 2003
Liver-derived insulin-like growth factor-I is involved in the regulation of blood pressure in
mice.

Åsa Tivesten, Entela Bollano, Irene Andersson, Sharyn M. Fitzgerald, Kenneth Caidahl, Klara Sjögren, Ole Skøtt, Jun-Li Liu, Reza Mobini, Olle Isaksson, John-Olov Jansson, Claes Ohlsson, Göran Bergström, Jörgen Isgaard
Endocrinology - 2002
Interleukin-6-deficient mice develop mature-onset
obesity.

Ville Wallenius, Kristina Wallenius, Bo Ahrén, Mats Rudling, Hans Carlsten, Suzanne L. Dickson, Claes Ohlsson, John-Olov Jansson
Nature medicine - 2002
Effects of liver-derived insulin-like growth factor I on bone metabolism in
mice.

Klara Sjögren, Matilda Sheng, Sofia Movérare, Jun-Li Liu, Kristina Wallenius, Jan Törnell, Olle Isaksson, John-Olov Jansson, Subburaman Mohan, Claes Ohlsson
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2002
A transgenic model to determine the physiological role of liver-derived insulin-like growth factor
I.

Klara Sjögren, John-Olov Jansson, Olle Isaksson, Claes Ohlsson
Minerva endocrinologica - 2002
A model for tissue-specific inducible insulin-like growth factor-I (IGF-I) inactivation to determine the physiological role of liver-derived
IGF-I.

Klara Sjögren, John-Olov Jansson, Olle Isaksson, Claes Ohlsson
Endocrine - 2002
Retarded liver growth in interleukin-6-deficient and tumor necrosis factor receptor-1-deficient
mice.

Ville Wallenius, Kristina Wallenius, Masanori Hisaoka, Jonas Sandstedt, Claes Ohlsson, M Kopf, John-Olov Jansson
Endocrinology - 2001
Liver-derived IGF-I regulates GH secretion at the pituitary level in
mice.

Kristina Wallenius, Klara Sjögren, X D Peng, S Park, Ville Wallenius, J L Liu, M. Umaerus, H Wennbo, Olle Isaksson, L Frohman, R Kineman, Claes Ohlsson, John-Olov Jansson
Endocrinology - 2001
Effects of growth hormone and its secretagogues on
bone.

Johan Svensson, S Lall, Suzanne L. Dickson, Bengt-Åke Bengtsson, J Rømer, I Ahnfelt-Rønne, Claes Ohlsson, John-Olov Jansson
Endocrine - 2001
The somatomedin hypothesis revisited in a transgenic
model.

Olle Isaksson, Claes Ohlsson, Klara Sjögren, Kristina Wallenius, John-Olov Jansson
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 2001
Liver-derived IGF-I is of importance for normal carbohydrate and lipid
metabolism.

Klara Sjögren, Kristina Wallenius, J L Liu, Mohammad Bohlooly-Yeganeh, G Pacini, L Svensson, Jan Törnell, Olle Isaksson, Bo Ahrén, John-Olov Jansson, Claes Ohlsson
Diabetes - 2001
Possible roles of insulin-like growth factor in regulation of physiological and pathophysiological liver
growth.

Stanko Skrtic, Kristina Wallenius, Klara Sjögren, Olle Isaksson, Claes Ohlsson, John-Olov Jansson
Hormone research - 2001
Metabolic functions of liver-derived (endocrine) insulin-like growth factor
I.

Olle Isaksson, John-Olov Jansson, Klara Sjögren, Claes Ohlsson
Hormone research - 2001
Growth hormone (GH)-independent stimulation of adiposity by GH
secretagogues.

S Lall, L Y Tung, Claes Ohlsson, John-Olov Jansson, Suzanne L. Dickson
Biochemical and biophysical research communications - 2001
Growth hormone induces CCAAT/enhancer binding protein alpha (C/EBPalpha) in cultured rat
hepatocytes.

P Strand, L Carlsson, Katarina Rask, Stanko Skrtic, S Ekberg, L Hedin, Jan Oscarsson, John-Olov Jansson
Journal of hepatology - 2000
The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female
rats.

Johan Svensson, S Lall, Suzanne L. Dickson, Bengt-Åke Bengtsson, J Rømer, I Ahnfelt-Rønne, Claes Ohlsson, John-Olov Jansson
The Journal of endocrinology - 2000
The relative importance of endocrine versus autocrine/paracrine insulin-like growth factor-I in the regulation of body
growth.

Claes Ohlsson, Klara Sjögren, John-Olov Jansson, Olle Isaksson
Pediatric nephrology (Berlin, Germany) - 2000
Effects of growth hormone and insulinlike growth factor-I on body growth and adult bone
metabolism.

Claes Ohlsson, John-Olov Jansson, Olle Isaksson
Current opinion in rheumatology - 2000
Treatment of obese subjects with the oral growth hormone secretagogue MK-677 affects serum concentrations of several lipoproteins, but not
lipoprotein(a).

Johan Svensson, John-Olov Jansson, Malin Ottosson, Gudmundur Johannsson, M R Taskinen, Olov Wiklund, Bengt-Åke Bengtsson
The Journal of clinical endocrinology and metabolism - 1999
Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in
mice.

Klara Sjögren, J L Liu, K Blad, Stanko Skrtic, Olle Vidal, Ville Wallenius, D LeRoith, Jan Törnell, Olle Isaksson, John-Olov Jansson, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 1999
Treatment with the oral growth hormone secretagogue MK-677 increases markers of bone formation and bone resorption in obese young
males.

Johan Svensson, Claes Ohlsson, John-Olov Jansson, G Murphy, D Wyss, D Krupa, K Cerchio, W Polvino, B Gertz, D J Baylink, Subburaman Mohan, Bengt-Åke Bengtsson
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1998
Topical zinc oxide treatment increases endogenous gene expression of insulin-like growth factor-1 in granulation tissue from porcine
wounds.

Peter Tarnow, M Agren, H Steenfos, John-Olov Jansson
Scandinavian journal of plastic and reconstructive surgery and hand surgery / Nordisk plastikkirurgisk forening [and] Nordisk klubb for handkirurgi - 1994
Increased gene expression of scatter factor-hepatocyte growth factor and basic fibroblast growth factor in granulation tissue in the
rat.

H Steenfos, Peter Tarnow, M Aram, T Nakamura, John-Olov Jansson
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society - 1993