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John-Olov Jansson

Professor

John-Olov Jansson
Professor
john-olov.jansson@medic.gu.se
+46 31 786 3526
0739-011122

Room number: 3413
Postal Address: Box 432, 40530 Göteborg
Visiting Address: Medicinaregatan 11 , 41390 Göteborg


Department of Physiology at Institute of Neuroscience and Physiology (More Information)
Box 432
405 30 Göteborg
Visiting Address: Medicinaregatan 11-13 , 413 90 Göteborg

About John-Olov Jansson

Research group
Immunometabolism Group

Teaching
Endocrinology for medical students and pharmacy students for more than 10 years. Since 2009 course leader for “BF2”, a course introducing scientific techniques and principles to medical students,

Research interest
Importance of brain components of the immune system, such as interleukin-6 (IL-6) och IL-1, for regulation of body fat.

Ongoing research / projects
We have recently found that Glucagon-like peptide-1 (GLP-1) suppresses body fat mass via interleukin-6 (IL-6) in the brain. This is a great interest since we have long-term interest in the metaolic of IL-6 and since GLP-1 analogues, such as exendin-4 (Byetta sand Bydureon) and liraglutide (Victoza and Saxenda) are widely used for treatment of type 2 diabetes and obesity. Surprisingly little has been known about the mechanism of action of this important group of drugs.

Related publications (PubMed):


 

Latest publications

Disentangling the genetics of lean mass
D. Karasik, M. C. Zillikens, Y. H. Hsu, A. Aghdassi, K. Akesson et al.
American Journal of Clinical Nutrition, Journal article 2019
Journal article

Hyperandrogenism and insulin resistance contribute to hepatic steatosis and inflammation in female rat liver.
Yuehui Zhang, Fanci Meng, Xiaoyan Sun, Xue Sun, Min Hu et al.
Oncotarget, Journal article 2018
Journal article

Body weight homeostat that regulates fat mass independently of leptin in rats and mice.
John-Olov Jansson, Vilborg Palsdottir, Daniel Hägg, Erik Schéle, Suzanne L. Dickson et al.
Proceedings of the National Academy of Sciences of the United States of America, Journal article 2018
Journal article

Deficiency of liver-derived insulin-like growth factor-I (IGF-I) does not interfere with the skin wound healing rate
I. R. Botusan, X. Zheng, S. Narayanan, J. Grünler, V. G. Sunkari et al.
PLoS ONE, Journal article 2018
Journal article

Reply to Lund: Where does the gravitostat fit in?
Claes Ohlsson, John-Olov Jansson
Proceedings of the National Academy of Sciences of the United States of America, Journal article 2018
Journal article

Showing 91 - 99 of 99

2000

1999

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice.
Klara Sjögren, J L Liu, K Blad, Stanko Skrtic, Olle Vidal et al.
Proceedings of the National Academy of Sciences of the United States of America, Journal article 1999
Journal article

1998

Treatment with the oral growth hormone secretagogue MK-677 increases markers of bone formation and bone resorption in obese young males.
Johan Svensson, Claes Ohlsson, John-Olov Jansson, G Murphy, D Wyss et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Journal article 1998
Journal article

1994

Topical zinc oxide treatment increases endogenous gene expression of insulin-like growth factor-1 in granulation tissue from porcine wounds.
Peter Tarnow, M Agren, H Steenfos, John-Olov Jansson
Scandinavian journal of plastic and reconstructive surgery and hand surgery / Nordisk plastikkirurgisk forening [and] Nordisk klubb for handkirurgi, Journal article 1994
Journal article

1993

Increased gene expression of scatter factor-hepatocyte growth factor and basic fibroblast growth factor in granulation tissue in the rat.
H Steenfos, Peter Tarnow, M Aram, T Nakamura, John-Olov Jansson
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, Journal article 1993
Journal article

Showing 91 - 99 of 99

Page Manager: Annie Sundling|Last update: 5/6/2015
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