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Håkan Billig


Håkan Billig
+46 31 786 3534

Room number: 3408
Postal Address: Box 432, 40530 Göteborg
Visiting Address: Medicinaregatan 11 , 41390 Göteborg

Department of Physiology at Institute of Neuroscience and Physiology (More Information)
Box 432
405 30 Göteborg
Visiting Address: Medicinaregatan 11-13 , 413 90 Göteborg

About Håkan Billig

Research group

Physiology of the Fallopian Tube and Ectopic Pregnancy

Research interest

Female reproductive endocrinology has remained my primary research interest throughout my research career I have had the opportunity to work on several levels: molecular, cellular, systemic and both in experimental animal models as well in clinical settings and patient materials.

My research focus has developed based on the knowledge we have acquired and in parallel with the fast evolving international research in our and adjacent fields of research and with introduction of new techniques:

  • ovarian metabolism (-1988)
  • growth factor and GH effects on reproduction (1988-1995)
  • follicular development and gonadal apoptosis (1990-2009)
  • function of and metabolic regulation by prolactin on metabolism (2000-2011)
  • progesterone and estrogen receptor subtype regulation and function in reproductive tissues (2003-2012)
  • Fallopian tube physiology and tubal ectopic pregnancy (2006-2012)

Latest publications

Hyperandrogenism and insulin resistance modulate gravid uterine and placental ferroptosis in PCOS-like rats.
Yuehui Zhang, Min Hu, Wenyan Jia, Guoqi Liu, Jiao Zhang et al.
The Journal of endocrinology, Journal article 2020
Journal article

Hyperandrogenism and insulin resistance induce gravid uterine defects in association with mitochondrial dysfunction and aberrant ROS production.
Min Hu, Yuehui Zhang, Xiaozhu Guo, Wenyan Jia, Guoqi Liu et al.
American journal of physiology. Endocrinology and metabolism, Journal article 2019
Journal article

Hyperandrogenism and insulin resistance contribute to hepatic steatosis and inflammation in female rat liver.
Yuehui Zhang, Fanci Meng, Xiaoyan Sun, Xue Sun, Min Hu et al.
Oncotarget, Journal article 2018
Journal article

Endometrial progesterone receptor isoforms in women with polycystic ovary syndrome
Min Hu, Juan Li, Yuehui Zhang, Xin Li, Mats Brännström et al.
American Journal of Translational Research, Journal article 2018
Journal article

Uterine progesterone signaling is a target for metformin therapy in PCOS-like rats.
Min Hu, Yuehui Zhang, Jiaxing Feng, Xue Xu, Jiao Zhang et al.
The Journal of endocrinology, Journal article 2018
Journal article

Showing 21 - 30 of 85


The onset of human ectopic pregnancy demonstrates a differential expression of miRNAs and their cognate targets in the Fallopian tube
Yi Feng, S. Zou, Birgitta Weijdegård, J. Chen, Q. Cong et al.
International Journal of Clinical and Experimental Pathology, Journal article 2014
Journal article

Endometrial progesterone resistance and PCOS
Xin Li, Yi Feng, Jin-Fang Lin, Håkan Billig, Linus Ruijin Shao
Journal of Biomedical Science. 2014 Jan 09;21(1):2, Review article 2014
Review article


Linking DNA methylation to the onset of human tubal ectopic pregnancy.
Lei Wang, Yi Feng, Shien Zou, Mats Brännström, Lin He et al.
American journal of translational research, Journal article 2013
Journal article

Showing 21 - 30 of 85

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