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Michael Ashton


Michael Ashton
+46 31 786 3412

Postal Address: Box 431, 40530 Göteborg
Visiting Address: Medicinaregatan 13 , 41390 Göteborg

Department of Pharmacolgy at Institute of Neuroscience and Physiology (More Information)
Box 431
405 30 Göteborg
Fax: +46 31821795
Visiting Address: Medicinaregatan 11-13 , 413 90 Göteborg

About Michael Ashton

Latest publications

Simultaneous quantification of four first line antitubercular drugs and metabolites in human plasma by hydrophilic interaction chromatography and tandem mass spectrometry
Jesper Sundell, E. Bienvenu, Sofia Birgersson, Angela Äbelö, Michael Ashton et al.
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, Journal article 2019
Journal article

Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis
F. Kloprogge, L. Workman, S. Borrmann, M. Tekete, G. Lefevre et al.
Plos Medicine, Journal article 2018
Journal article

MRP2/ABCC2 C1515Y polymorphism modulates exposure to lumefantrine during artemether-lumefantrine antimalarial therapy
K. Vos, C. Lo Sciuto, R. Piedade, Michael Ashton, A. Bjorkman et al.
Pharmacogenomics, Journal article 2017
Journal article

Artemether-lumefantrine coadministration with antiretrovirals; population pharmacokinetics and dosing implications
Richard Höglund, Pauline Byakika‐Kibwika, Mohammed Lamorde, Concepta Merry, Michael Ashton et al.
British Journal of Clinical Pharmacology, Journal article 2015
Journal article

Population pharmacokinetics of artesunate and dihydroartemisinin during long-term oral administration of artesunate to patients with metastatic breast cancer.
Therese Ericsson, Antje Blank, Cornelia von Hagens, Michael Ashton, Angela Abelö
European Journal of Clinical Pharmacology, Journal article 2014
Journal article

Showing 51 - 60 of 60


Simultaneous enantiospecific separation and quantitation of mephenytoin and its metabolites nirvanol and 4'-hydroxymephenytoin in human plasma by liquid chromatography.
Britt Jansson, Ulrika S H Simonsson, Michael Ashton
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, Journal article 2003
Journal article

Artemisinin autoinduction is caused by involvement of cytochrome P450 2B6 but not 2C9.
Ulrika S H Simonsson, Britt Jansson, Trinh Ngoc Hai, Dinh Xuan Huong, Gunnel Tybring et al.
Clinical pharmacology and therapeutics, Journal article 2003
Journal article

Characterisation of the human liver in vitro metabolic pattern of artemisinin and auto-induction in the rat by use of nonlinear mixed effects modelling.
Ulrika S H Svensson, Mika Mäki-Jouppila, Kurt-Jürgen Hoffmann, Michael Ashton
Biopharmaceutics & drug disposition, Journal article 2003
Journal article


Artemisinin pharmacokinetics and efficacy in uncomplicated-malaria patients treated with two different dosage regimens.
Toufigh Gordi, Dinh Xuan Huong, Trinh Ngoc Hai, Nguyen Thi Nieu, Michael Ashton
Antimicrobial agents and chemotherapy, Journal article 2002
Journal article

Population pharmacokinetic and pharmacodynamic modelling of artemisinin and mefloquine enantiomers in patients with falciparum malaria.
Ulrika S H Svensson, Hassan Alin, Mats O Karlsson, Yngve Bergqvist, Michael Ashton
European journal of clinical pharmacology, Journal article 2002
Journal article

Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (Malarone) when taken as chemoprophylaxis.
Mita M Thapar, Michael Ashton, Niklas Lindegårdh, Yngve Bergqvist, Sabina Nivelius et al.
European journal of clinical pharmacology, Journal article 2002
Journal article


In vitro evidence for auto-induction of artemisinin metabolism in the rat.
S Gupta, U S Svensson, Michael Ashton
European journal of drug metabolism and pharmacokinetics, Journal article 2001
Journal article

Multiple dose study of interactions between artesunate and artemisinin in healthy volunteers.
S Q Zhang, T N Hai, K F Ilett, D X Huong, T M Davis et al.
British journal of clinical pharmacology, Journal article 2001
Journal article

Showing 51 - 60 of 60

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