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Hydrocephalus and CSF dynamic disorders

Principal Investigators: Carsten Wikkelsø and Mats Tullberg

The aims of our research project are to clarify pathophysiological and clinical aspects of disorders affecting cerebral spinal fluid (CSF) dynamics, e.g. hydrocephalus and intra cranial arachnoid cysts.

Hydrocephalus is a common disorder in the elderly (more than 2% of individuals older than 70 years) and one of the few treatable dementia disorders in the elderly. It also causes gait problems and incontinence. Treatment is effective; significantly improving more than 80% of the affected patients. Undiagnosed patients deteriorate irreversibly. Many patients are unfortunately undiagnosed. Knowledge of symptoms and signs, risk factors and pathophysiological mechanisms are crucial for identification and treatment.

Arachnoid cysts are common findings (around 2%) in the general population. The relationship between accidentallydiagnosed cysts and symptoms and signs is dubious. Also the effect of treatment is a matter of debate requiring research.

Chiari-I malformation is characterized by a caudal descent of the cerebellum into the spinal canal. The project aims to describe pathophysiological aspects of the CSF dynamics and relation to symptoms and signs and quality of life.

Principal Investigators

Porträttfoto Carsten Wikkelsö

Carsten Wikkelsø

Professor Emeritus

E-mail: carsten.wikkelso@neuro.gu.se


Porträttfoto Mats Tullberg

Mats Tullberg

Assistant Professor

E-mail: mats.tullberg@neuro.gu.se
Mobile phone: +46 76-867 26 18

Page Manager: Katinka Almrén|Last update: 6/28/2017

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