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Epilepsy surgery - methodological development and treatment outcomes


Principal Investigator: Kristina Malmgren

For selected persons with drug-resistant focal epilepsy, surgical treatment is an efficient and well-established treatment. Epilepsy surgery may be resective, i e, the area of the brain in which the seizures start is surgically removed. The aim is for the patient to become seizure free, or have a significant reduction in seizure frequency. In resective epilepsy surgery it is important to define the seizure onset zone and to tailor the planned operation accordingly. Epilepsy surgery can also be palliative, where the goal is limited to reduce or abolish a certain kind of seizures. The most common procedure is callosotomy, where the connection between the hemispheres is divided in order to prevent rapid spread of seizures and reduce the number of so-called drop attacks.

Our research includes methodological development of neuroimaging as well as treatment outcomes. We study the outcomes of epilepsy surgery both in our own consecutive cohort of patients and also for all patients operated in Sweden through the Swedish National Epilepsy Surgery Register, which contains data for all patients operated since 1990.

We investigate many relevant outcomes: seizure outcome and its predictors both short- and long-term (follow-up up to 20 years after surgery); complications; cognitive effects; vocational outcome; mortality and comorbidities; health-related quality of life; personal perceptions. We use both quantitative and qualitative methods.

 

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Contact information

Photo of Kristina Malmgren

Kristina Malmgren

Professor

E-mail: kristina.malmgren@neuro.gu.se
Tel: +46 31-342 27 63

Page Manager: Katinka Almrén|Last update: 10/18/2018
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Denna text är utskriven från följande webbsida:
http://neurophys.gu.se/english/departments/clinical_neuroscience_and_rehabilitation/neuroscience/epilepsy/epilepsy-surgery/?languageId=100001&disableRedirect=true&returnUrl=http%3A%2F%2Fneurophys.gu.se%2Fsektioner%2Fklinisk-neurovetenskap%2Fforskning%2Fneurologi%2Fthe-epilepsy-research-group%2Fepilepsikirurgi%2F
Utskriftsdatum: 2019-11-17