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Eric Hanse

“What we learnt, and what we will possibly learn, about the brain’s network by means of methods from neurophysiology”

Eric HanseThe lecture will recapitulate some of the basic neurophysiological concepts from ion channels, via synaptic transmission and the action potential to oscillatory network activity. In this context I will also discuss the concepts of plasticity and modulation of neuronal excitability. I will briefly discuss current electrophysiological methods and continue with methods such as optical recording and optical stimulation, which are now rapidly developing and providing entirely new approaches to study the function of the brain’s network. I will use spatial learning and memory as an example of what we learnt, and what we will possibly learn, about the brain’s network.


Eric Hanse is professor in neurophysiology at the Sahlgrenska Academy, University of Gothenburg. Using electrophysiological methods he has studied basic aspects of synaptic transmission and synaptic plasticity mainly in the hippocampus.

Suggested reading

  • Hochbaum et al (2014) All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins Nature Methods 11: 825-833
  • Grosenick et al (2015) Closed-loop and activity-guided optogenetic control Neuron 86:106-139
  • Yuste (2015) From the neuron doctrine to neural networks Nature Reviews Neuroscience 16: 487-497
  • Lisman (2015) The challenge of understanding the brain: where we stand in 2015 Neuron 86:864-882
  • Hanse et al (2013) AMPA silent synapses in brain development and pathology Nature Review Neuroscience 14: 839-850

Conference Presentation

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Page Manager: Daniel Ruhe|Last update: 8/21/2015

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